Information about normal hepatic glucose metabolism may help to understand pathogenic
mechanisms underlying obesity and diabetes mellitus. In addition, liver glucose metabolism …

Each Association appointed at least one author to serve on the writing group. The Chair of
the writing group was appointed by the AASLD. Members of the writing group were not …

Disclaimer: This guideline is designed primarily as an educational resource for clinicians to
help them provide quality medical services. Adherence to this guideline is completely …

Technologies such as next-generation sequencing and chromosomal microarray have
advanced the understanding of the molecular pathogenesis of a variety of renal disorders …

Gluconeogenesis is a critical biosynthetic process that helps maintain whole-body glucose
homeostasis and becomes altered in certain medical diseases. We review gluconeogenic …

Glycogen storage disease type Ia (GSDIa) is caused by defective glucose-6-phosphatase, a
key enzyme in carbohydrate metabolism. Affected individuals cannot release glucose during …

BACKGROUND & AIMS: Hepatocellular adenomas (HCA) are benign liver tumors mainly
related to oral contraception and classified into 4 molecular subgroups: inflammatory (IHCA) …

Diabetes mellitus is the most well-known endocrine dilemma suffered by hundreds of million
people globally, with an annual mortality of more than one million people. This high mortality …

Background & Aims Glucose-6-phosphatase (G6Pase α, G6PC) deficiency, also known as
von Gierke's disease or GSDIa, is the most common glycogen storage disorder. It is …

Hepatic glucose and lipid metabolism are altered in metabolic disease (eg obesity,
metabolic syndrome, and Type 2 diabetes). Insulin-dependent regulation of glucose …