Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia,
intrauterine growth restriction, and placental abruption. Their timely and accurate recognition …

Preeclampsia is a common pregnancy complication which can have adverse impact on both
mother and baby. In addition to the short term effects, a large body of epidemiological …

Importance The risk of congenital heart defects in infants of women who had preeclampsia
during pregnancy is poorly understood, despite shared angiogenic pathways in both …

The placenta is a complex organ that influences prenatal growth and development, and
through fetal programming impacts postnatal health and well-being lifelong. Little …

Placental dysfunction underlies the cause of pregnancies complicated by preeclampsia. The
use of placental magnetic resonance imaging to provide an insight into the pathophysiology …

Introduction Hypoplastic left heart syndrome (HLHS) is a severe cardiovascular
malformation (CVM) associated with fetal growth abnormalities. Genetic and environmental …

Background: Congenital heart defects (CHDs) have been associated with placental
anomalies. The nature and the consequences of this association remain poorly understood …

Background: Both pregnant women carrying fetuses with heart defects and women with
hypertensive disorders of pregnancy often exhibit angiogenic imbalances, suggesting that …

Background Knowledge about extracardiac anomalies (ECA) in fetal congenital heart
disease (CHD) can improve our understanding of the developmental origins of various …

Preeclampsia is caused by placental impairment with increased expression of sFlt-1
(soluble fms-like tyrosine kinase 1) and decreased PlGF (placental growth factor); it has …