Hydrodynamic Delivery: Characteristics, Applications, and Technological Advances

T Suda, T Yokoo, T Kanefuji, K Kamimura, G Zhang… - Pharmaceutics, 2023 - mdpi.com
The principle of hydrodynamic delivery was initially used to develop a method for the
delivery of plasmids into mouse hepatocytes through tail vein injection and has been …

A humanized mouse model for adeno-associated viral gene therapy

M Barzi, T Chen, TJ Gonzalez, FP Pankowicz… - Nature …, 2024 - nature.com
Clinical translation of AAV-mediated gene therapy requires preclinical development across
different experimental models, often confounded by variable transduction efficiency. Here …

Edición genómica en ratón basada en la electroporación de CRISPR/Cas9 en cigotos. Aplicación al estudio del síndrome de mano hendida

S Lucas Toca - 2022 - repositorio.unican.es
Discovery of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/Cas9
has supposed a huge revolution on the genetic engineering field. We have established a …