The hypothalamus contains the highest diversity of neurons in the brain. Many of these
neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner …

Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

The RFamide neuropeptide 26RFa was first isolated from the brain of the European green
frog on the basis of cross‐reactivity with antibodies raised against bovine neuropeptide FF …

Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis during chronic stress is
essential for depression neurobiology. As the latest member of the RFamide peptide family …

According to the World Health Organization report published in 2016, 650 million people
worldwide suffer from obesity, almost three times more than in 1975. Obesity is defined as …

The RFamide peptide family is a group of proteins that share a common C-terminal arginine–
phenylalanine–amide motif. To date, the family comprises five groups in mammals …

This mini-review deals with the neuropeptide 26RFa (or QRFP) which is a member of the
RFamide peptide family discovered simultaneously by three groups in 2003. 26RFa (or its N …

How the hypothalamus transmits hunger information to other brain regions to govern whole
brain function to orchestrate feeding behavior has remained largely unknown. Our present …

Background: Obesity and type 2 diabetes are strongly associated pathologies, currently
considered as a worldwide epidemic problem. Understanding the mechanisms that drive the …

26RFa is a neuropeptide that activates the rhodopsin-like G protein-coupled receptor
QRFPR/GPR103. This peptidergic system is involved in the regulation of a wide array of …