Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays
crucial roles in tumor development and biology. Cancer progression can be regulated by …

The mucosal surfaces that form the boundary between the external environment and the
underlying tissue are protected by a mucus barrier. Mucin glycoproteins, both secreted and …

Parasitic helminths (worms) co-evolved with vertebrate immune systems to enable long-term
survival of worms in infected hosts. Among their survival strategies, worms use their glycans …

Fasciola hepatica, commonly known as liver fluke, is a trematode that causes Fasciolosis in
ruminants and humans. The outer tegumental coat of F. hepatica (FhTeg) is a complex …

Helminths express various carbohydrate-containing glycoconjugates on their surface, and
they release glycan-rich excretion/secretion products that can be very important in their life …

A large family of UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferases
(ppGalNAc Ts) catalyzes the first step of mucin-type protein O-glycosylation by transferring …

An adverse relationship between some parasite infections and cancer in the human
population has been reported by different research groups. Anticancer activity of some …

The Tn antigen is a carbohydrate antigen expressed in most carcinomas, during
embryogenesis, on pathogenic parasites, and on HIV. It has been evaluated extensively as …

Simple mucin‐type O‐glycan structures, such as Tn, TF, sialyl‐Tn and Tk antigens, are
among of the most specific human cancer‐associated structures. These antigens are …

The tumor-associated Tn antigen has been investigated extensively as a biomarker and
therapeutic target. Cancer vaccines containing the Tn antigen as a single tumor antigen or …