Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells

MM Mostafa, MM Amin, MY Zakaria, MA Hussein… - Pharmaceutics, 2023 - mdpi.com
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …

Application of Box–Behnken design and desirability function in the development and optimization of self-nanoemulsifying drug delivery system for enhanced …

P Yadav, V Rastogi, A Verma - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background This study is focused on developing and optimizing a self-nanoemulsifying drug
delivery system (SNEDDS) of BCS class II drug (ezetimibe) through Box–Behnken design …

Cardioprotective Effect of Rumex vesicarius Linn. Leaf Extract against Catecholamine-Induced Cardiotoxicity

IA Khan, M Hussain, N Hussain, AM Alqahtani… - Molecules, 2022 - mdpi.com
Rumex vesicarius (L.) is a folklore medicinal herb that has been used for centuries to cure
cardiovascular diseases. The present work was carefully designed to ascertain the …

Cardioprotective effect of thymol against adrenaline-induced myocardial injury in rats

SA El-Marasy, SA El Awdan, A Hassan, HMI Abdallah - Heliyon, 2020 - cell.com
Cardiovascular disease represents a vital global disease burden. This study aims to assess
the possible cardioprotective effect of thymol against adrenaline-induced myocardial injury …

Jasminum sambac: A Potential Candidate for Drug Development to Cure Cardiovascular Ailments

IA Khan, M Hussain, SH Munawar, MO Iqbal, S Arshad… - Molecules, 2021 - mdpi.com
Jasminum sambac (L.) is a South Asian folkloric medicinal plant that has traditionally been
used to treat cardiovascular problems. The current investigation was meticulously organized …

[HTML][HTML] Association between activities of SOD, MDA and Na+-K+-ATPase in peripheral blood of patients with acute myocardial infarction and the complication of …

Y Yin, W Han, Y Cao - Hellenic Journal of Cardiology, 2019 - Elsevier
Objective To investigate the changes of ambulatory electrocardiography and peripheral
blood SOD, MDA and Na+-K+-ATP enzymes in patients of acute myocardial infarction (AMI) …

Quality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on Nelfinavir mesylate

S Kamboj, V Rana - International journal of pharmaceutics, 2016 - Elsevier
Poor aqueous solubility and moderate permeability of Nelfinavir mesylate (NFM) leads to
high variability in absorption after oral administration. To improve the solubility and …

Pharmacological Justification for the Medicinal Use of Plumeria rubra Linn. in Cardiovascular Disorders

IA Khan, M Hussain, SK Syed, M Saadullah… - Molecules, 2021 - mdpi.com
Plumeria rubra (L.) is a traditional folkloric medicinal herb used to treat cardiovascular
disorders. The present investigation was methodically planned to investigate the …

Nanotechnology‐Based Strategies for Extended‐Release Delivery of Angiotensin Receptor Blockers (ARBs): A Comprehensive Review

B Haji Ali, M Shirvaliloo, S Fathi‐Karkan… - Chemistry & …, 2023 - Wiley Online Library
There has been a significant shift in the perception of hypertension as an important
contributor to the global disease burden. Approximately 6% and 8% of pregnancies are …

Modulatory effect of Ovothiol‐A on myocardial infarction induced by epinephrine in rats

EN Mohammed, AM Soliman… - Journal of Food …, 2022 - Wiley Online Library
Myocardial infarction (MI) is one of the most prevalent disorders seen in clinical practice, and
its prevalence has risen dramatically in the last decade. Ovothiol‐A is a natural product …