Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …
J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
Branched chain amino acids
Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here
the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have …
the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have …
Branched chain amino acids in metabolic disease
Abstract Purpose of Review Elevations in circulating branched chain amino acids (BCAAs)
have gained attention as potential contributors to the development of insulin resistance and …
have gained attention as potential contributors to the development of insulin resistance and …
Why are branched-chain amino acids increased in starvation and diabetes?
M Holeček - Nutrients, 2020 - mdpi.com
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are increased in
starvation and diabetes mellitus. However, the pathogenesis has not been explained. It has …
starvation and diabetes mellitus. However, the pathogenesis has not been explained. It has …
Branched‐chain amino acids promote endothelial dysfunction through increased reactive oxygen species generation and inflammation
O Zhenyukh, M González‐Amor… - Journal of cellular …, 2018 - Wiley Online Library
Branched‐chain amino acids (BCAA: leucine, isoleucine and valine) are essential amino
acids implicated in glucose metabolism and maintenance of correct brain function. Elevated …
acids implicated in glucose metabolism and maintenance of correct brain function. Elevated …
Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits
Mitochondria (MT), the major site of cellular energy production, are under dual genetic
control by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA) …
control by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA) …
Plasma branched chain/aromatic amino acids, enriched Mediterranean diet and risk of type 2 diabetes: case-cohort study within the PREDIMED Trial
Aims/hypothesis Branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs)
are associated with type 2 diabetes. However, repeated measurements of BCAA/AAA and …
are associated with type 2 diabetes. However, repeated measurements of BCAA/AAA and …
Effects of Qijian mixture on type 2 diabetes assessed by metabonomics, gut microbiota and network pharmacology
K Gao, R Yang, J Zhang, Z Wang, C Jia, F Zhang… - Pharmacological …, 2018 - Elsevier
Qijian mixture, a new traditional Chinese medicine (TCM) formula comprising of Astragalus
membranaceus, Ramulus euonymi, Coptis chinensis and Pueraria lobata, was designed to …
membranaceus, Ramulus euonymi, Coptis chinensis and Pueraria lobata, was designed to …
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI
BW van der Kolk, S Saari, A Lovric, M Arif… - Cell Reports …, 2021 - cell.com
Tissue-specific mechanisms prompting obesity-related development complications in
humans remain unclear. We apply multiomics analyses of subcutaneous adipose tissue and …
humans remain unclear. We apply multiomics analyses of subcutaneous adipose tissue and …
Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men
Aims/hypothesis Obesity and insulin resistance may be associated with elevated plasma
concentration of branched-chain amino acids (BCAAs) and impaired BCAA metabolism …
concentration of branched-chain amino acids (BCAAs) and impaired BCAA metabolism …