Alcohol, injury, and cellular immunity

KAN Messingham, DE Faunce, EJ Kovacs - Alcohol, 2002 - Elsevier
It is widely accepted that alcohol exposure is a causative factor in the occurrence of burn or
other traumatic injury. It is less well known that individuals who have consumed alcohol …

Role of the gastrointestinal tract in burn sepsis

A Gosain, RL Gamelli - The Journal of burn care & rehabilitation, 2005 - academic.oup.com
During the last 50 years, our understanding of the role of the gastrointestinal tract as a first-
line defense against the development of postburn sepsis has increased dramatically …

LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF‐κB/NLRP3 inflammasome pathway

M Ma, Y Pei, X Wang, J Feng, Y Zhang… - Cell proliferation, 2019 - Wiley Online Library
Objectives The correlations between long non‐coding RNAs (lncRNAs) and diverse
mammal diseases have been clarified by many researches, but the cognition about bovine …

Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice

Y Kimura, M Sumiyoshi, K Kawahira… - British journal of …, 2006 - Wiley Online Library
1 We recently demonstrated that ginsenoside Rb1 (C54H92O23, molecular weight 1108)
isolated from ginseng, when intravenously infused into rats with permanent middle cerebral …

Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism

Y Kimura, M Sumiyoshi, K Samukawa, N Satake… - European Journal of …, 2008 - Elsevier
Some reports published from 1967 to 1999 describe the use of ointments containing high
doses (0.1 to 0.2%, w/w) C. asiataica herb extracts to enhance wound repair. Lower doses at …

Acute immunomodulatory effects of binge alcohol ingestion

M Afshar, S Richards, D Mann, A Cross, GB Smith… - Alcohol, 2015 - Elsevier
Background Blood alcohol is present in a third of trauma patients and has been associated
with organ dysfunction. In both human studies and in animal models, it is clear that alcohol …

Gut-associated lymphoid T cell suppression enhances bacterial translocation in alcohol and burn injury

MA Choudhry, N Fazal, M Goto… - American Journal …, 2002 - journals.physiology.org
The mechanism of alcohol-mediated increased infection in burn patients remains unknown.
With the use of a rat model of acute alcohol and burn injury, the present study ascertained …

Impaired intestinal immunity and barrier function: a cause for enhanced bacterial translocation in alcohol intoxication and burn injury

MA Choudhry, SN Rana, MJ Kavanaugh, EJ Kovacs… - Alcohol, 2004 - Elsevier
Alcohol intoxication is being recognized increasingly as the major factor in pathogenesis
after burn injury. Findings from multiple studies support the suggestion that, in comparison …

Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury

A Zahs, MD Bird, L Ramirez… - American Journal …, 2012 - journals.physiology.org
Laboratory evidence suggests that intestinal permeability is elevated following either binge
ethanol exposure or burn injury alone, and this barrier dysfunction is further perturbed when …

Sex differences and estrogen modulation of the cellular immune response after injury

MD Bird, J Karavitis, EJ Kovacs - Cellular immunology, 2008 - Elsevier
Cell-mediated immunity is extremely important for resolution of infection and for proper
healing from injury. However, the cellular immune response is dysregulated following …