Physiology of sedentary behavior
Sedentary behaviors (SB) are characterized by low energy expenditure while in a sitting or
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …
Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies
Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …
The impact of bed rest on human skeletal muscle metabolism
Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal
and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we …
and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we …
Single‐leg disuse decreases skeletal muscle strength, size, and power in uninjured adults: a systematic review and meta‐analysis
N Preobrazenski, J Seigel, S Halliday… - Journal of cachexia …, 2023 - Wiley Online Library
We aimed to quantify declines from baseline in lower limb skeletal muscle size and strength
of uninjured adults following single‐leg disuse. We searched EMBASE, Medline, CINAHL …
of uninjured adults following single‐leg disuse. We searched EMBASE, Medline, CINAHL …
[HTML][HTML] (-)-Epicatechin and its colonic metabolite hippuric acid protect against dexamethasone-induced atrophy in skeletal muscle cells
Cocoa flavanols have been shown to improve muscle function and may offer a novel
approach to protect against muscle atrophy. Hippuric acid (HA) is a colonic metabolite of (-) …
approach to protect against muscle atrophy. Hippuric acid (HA) is a colonic metabolite of (-) …
Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men
Short-term disuse leads to muscle loss driven by lowered daily myofibrillar protein synthesis
(MyoPS). However, disuse commonly results from muscle damage, and its influence on …
(MyoPS). However, disuse commonly results from muscle damage, and its influence on …
A focus on leucine in the nutritional regulation of human skeletal muscle metabolism in ageing, exercise and unloading states
Muscle protein synthesis (MPS) and muscle protein breakdown (MPB) are influenced
through dietary protein intake and physical (in) activity, which it follows, regulate skeletal …
through dietary protein intake and physical (in) activity, which it follows, regulate skeletal …
[HTML][HTML] Elucidating the underlying mechanism of amino acids to regulate muscle protein synthesis: effect on human health
X Lv, C Zhou, Q Yan, Z Tan, J Kang, S Tang - Nutrition, 2022 - Elsevier
Maintaining muscle quality throughout life is crucial to human health and well-being. Muscle
is the most extensive form of protein storage in the human body; skeletal muscle mass is …
is the most extensive form of protein storage in the human body; skeletal muscle mass is …
No effect of five days of bed rest or short‐term resistance exercise prehabilitation on markers of skeletal muscle mitochondrial content and dynamics in older adults
RN Marshall, B Smeuninx, AP Seabright… - Physiological …, 2022 - Wiley Online Library
Bed rest (BR) results in significant impairments in skeletal muscle metabolism. Mitochondrial
metabolism is reportedly highly sensitive to disuse, with dysregulated fission‐fusion events …
metabolism is reportedly highly sensitive to disuse, with dysregulated fission‐fusion events …
Neuromuscular electrical stimulation resistance training enhances oxygen uptake and ventilatory efficiency independent of mitochondrial complexes after spinal cord …
The purpose of the study was to determine whether neuromuscular electrical stimulation
resistance training (NMES-RT)-evoked muscle hypertrophy is accompanied by increased …
resistance training (NMES-RT)-evoked muscle hypertrophy is accompanied by increased …