Biological monitoring of radiation exposure relies heavily on the quantification of
chromosome aberrations such as dicentrics and reciprocal translocations in the peripheral …

High linear energy transfer (LET) α particles are important with respect to the carcinogenic
risk associated with human exposure to ionizing radiation, most notably to radon and its …

Abstract Introduction Radium-223 dichloride ([223 Ra] RaCl 2), a radiopharmaceutical that
delivers α-particles to regions of bone metastatic disease, has been proven to improve …

Naturally occurring radon and its short lived progeny are the second leading cause of lung
cancer after smoking, and the main risk factor for non-smokers. The radon progeny, mainly …

It is well established that chromosomes exist in discrete territories (CTs) in interphase and
are positioned in a cell-type specific probabilistic manner. The relative localisation of …

Ionizing radiation causes chromosome aberrations, which are possible biomarkers to
assess space radiation cancer risks. Using the Monte Carlo codes Relativistic Ion Tracks …

Ionizing radiation generates DNA double-strand breaks (DSB) which, unless faithfully
repaired, can generate chromosomal rearrangements in hematopoietic stem and/or …

The aim of the present study was to perform comprehensive prenatal diagnosis using
various detection techniques on a fetus in a high‑risk pregnant woman, and to provide …

Whole-chromosome painting (WCP) typically involves the fluorescent staining of a small
number of chromosomes. Consequently, it is capable of detecting only a fraction of …

Abstract Purpose Adverse outcome pathways (AOPs) provide a modular framework for
describing sequences of biological key events (KEs) and key event relationships (KERs) …