Role of hormones in the pregnancy and sex‐specific outcomes to infections with respiratory viruses

O Cervantes, I Cruz Talavera, E Every… - Immunological …, 2022 - Wiley Online Library
Pregnant women infected with pathogenic respiratory viruses, such as influenza A viruses
(IAV) and coronaviruses, are at higher risk for mortality, hospitalization, preterm birth, and …

Port d'Entrée for respiratory infections–Does the influenza a virus pave the way for bacteria?

N Siemens, S Oehmcke-Hecht… - Frontiers in …, 2017 - frontiersin.org
Bacterial and viral co-infections of the respiratory tract are life-threatening and present a
global burden to the global community. Staphylococcus aureus, Streptococcus pneumoniae …

Distinct immune responses and virus shedding in pigs following aerosol, intra-nasal and contact infection with pandemic swine influenza A virus, A (H1N1) 09

JD Hemmink, SB Morgan, M Aramouni, H Everett… - Veterinary …, 2016 - Springer
Influenza virus infection in pigs is a major farming problem, causing considerable economic
loss and posing a zoonotic threat. In addition the pig is an excellent model for understanding …

Comparative Pathology of Animal Models for Influenza A Virus Infection

NM Kirk, Y Liang, H Ly - Pathogens, 2023 - mdpi.com
Animal models are essential for studying disease pathogenesis and to test the efficacy and
safety of new vaccines and therapeutics. For most diseases, there is no single model that …

Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection

M Charman, S McFarlane, JK Wojtus… - Frontiers in Cellular …, 2021 - frontiersin.org
The induction of antiviral effector proteins as part of a homeostatically controlled innate
immune response to infection plays a critical role in limiting the propagation and …

The characteristics of hDPP4 transgenic mice subjected to aerosol MERS coronavirus infection via an animal nose‐only exposure device

X Hao, Q Lv, F Li, Y Xu, H Gao - Animal Models and …, 2019 - Wiley Online Library
Abstract Background Middle East respiratory syndrome coronavirus (MERS‐CoV), which is
not fully understood in regard to certain transmission routes and pathogenesis and lacks …

Characterisation of particle size and viability of SARS-CoV-2 aerosols from a range of nebuliser types using a novel sampling technique

S Paton, S Clark, A Spencer, I Garratt, I Dinesh… - Viruses, 2022 - mdpi.com
Little is understood about the impact of nebulisation on the viability of SARS-CoV-2. In this
study, a range of nebulisers with differing methods of aerosol generation were evaluated to …

The marmoset as an animal model of influenza: Infection with A (H1N1) pdm09 and highly pathogenic A (H5N1) viruses via the conventional or tracheal spray route

K Iwatsuki-Horimoto, N Nakajima, M Kiso… - Frontiers in …, 2018 - frontiersin.org
To control infectious diseases in humans, it is important to understand the pathogenicity of
the infecting organism (s). Although non-human primates, such as cynomolgus and rhesus …

Distinct transcriptional responses to fatal Ebola virus infection in cynomolgus and rhesus macaques suggest species-specific immune responses

AN Pinski, KJ Maroney, A Marzi… - Emerging Microbes & …, 2021 - Taylor & Francis
Ebola virus (EBOV) is a negative single-stranded RNA virus within the Filoviridae family and
the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including …

In vivo models to study the pathogenesis of extra-respiratory complications of influenza A virus infection

E Veldhuis Kroeze, L Bauer, V Caliendo, D van Riel - Viruses, 2021 - mdpi.com
Animal models are an inimitable method to study the systemic pathogenesis of virus-
induced disease. Extra-respiratory complications of influenza A virus infections are not …