The role of AMPKα subunit in Alzheimer's disease: In-depth analysis and future prospects
L Xia, J Chen, J Huang, X Lin, J Jiang, T Liu, N Huang… - Heliyon, 2024 - cell.com
The AMP-activated protein kinase α (AMPKα) subunit is the catalytic subunit in the AMPK
complex, playing a crucial role in AMPK activation. It has two isoforms: AMPKα1 and …
complex, playing a crucial role in AMPK activation. It has two isoforms: AMPKα1 and …
[HTML][HTML] The six-transmembrane enzyme GDE2 is required for the release of molecularly distinct small extracellular vesicles from neurons
KT Shuler, J Llamas-Rodriguez, R Levy-Myers… - Cells, 2024 - mdpi.com
Extracellular vesicles (EVs) are implicated in a multitude of physiological and
pathophysiological processes in the nervous system; however, their biogenesis and cargoes …
pathophysiological processes in the nervous system; however, their biogenesis and cargoes …
[HTML][HTML] Vesicular Transport and Amyloids: The Growing Relationship
A Upadhyay - Biologics, 2024 - mdpi.com
Protein aggregation may lead to detrimental changes in brain and several other tissues.
Amyloids or large protein aggregates are formed in different brain areas under multiple …
Amyloids or large protein aggregates are formed in different brain areas under multiple …
Efficient enzyme‐free isolation of brain‐derived extracellular vesicles
A Matamoros‐Angles, E Karadjuzovic… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) have gained significant attention as pathology mediators and
potential diagnostic tools for neurodegenerative diseases. However, isolation of brain …
potential diagnostic tools for neurodegenerative diseases. However, isolation of brain …
Comment on “Extracellular Vesicles Slow Down Aβ (1–42) Aggregation by Interfering with the Amyloid Fibril Elongation Step”
M Shafiq, A Matamoros-Angles… - ACS Chemical …, 2024 - ACS Publications
Halipi et al. explored the impact of extracellular vesicles (EVs) on amyloid-β (Aβ)
aggregation. They concluded that EVs reduce Aβ aggregation, as seen by shorter and …
aggregation. They concluded that EVs reduce Aβ aggregation, as seen by shorter and …