Matrescence: lifetime impact of motherhood on cognition and the brain

ER Orchard, HJV Rutherford, AJ Holmes… - Trends in cognitive …, 2023 - cell.com
Profound environmental, hormonal, and neurobiological changes mark the transition to
motherhood as a major biosocial life event. Despite the ubiquity of motherhood, the …

Endogenous and exogenous estrogen exposures: how women's reproductive health can drive brain aging and inform Alzheimer's prevention

S Jett, N Malviya, E Schelbaum, G Jang… - Frontiers in Aging …, 2022 - frontiersin.org
After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …

Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's disease

C Barth, A Crestol, AMG de Lange… - The Lancet Diabetes & …, 2023 - thelancet.com
Despite widespread sex differences in prevalence and presentation of numerous illnesses
affecting the human brain, there has been little focus on the effect of endocrine ageing. Most …

Individual variations in 'brain age'relate to early-life factors more than to longitudinal brain change

D Vidal-Pineiro, Y Wang, SK Krogsrud, IK Amlien… - elife, 2021 - elifesciences.org
Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …

[HTML][HTML] Commentary: Correction procedures in brain-age prediction

AMG de Lange, JH Cole - NeuroImage: Clinical, 2020 - ncbi.nlm.nih.gov
3. Conclusions Two main conclusions can be drawn based on the examples in this
commentary: I) The method proposed by Behesti et al. provides age-bias correction that is …

[HTML][HTML] White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age …

D Beck, AMG de Lange, II Maximov, G Richard… - NeuroImage, 2021 - Elsevier
The macro-and microstructural architecture of human brain white matter undergoes
substantial alterations throughout development and ageing. Most of our understanding of …

Mind the gap: Performance metric evaluation in brain‐age prediction

AMG de Lange, M Anatürk, J Rokicki… - Human Brain …, 2022 - Wiley Online Library
Estimating age based on neuroimaging‐derived data has become a popular approach to
developing markers for brain integrity and health. While a variety of machine‐learning …

Brain-age prediction: A systematic comparison of machine learning workflows

S More, G Antonopoulos, F Hoffstaedter, J Caspers… - NeuroImage, 2023 - Elsevier
The difference between age predicted using anatomical brain scans and chronological age,
ie, the brain-age delta, provides a proxy for atypical aging. Various data representations and …

Women's neuroplasticity during gestation, childbirth and postpartum

M Paternina-Die, M Martínez-García… - Nature …, 2024 - nature.com
Pregnancy is a unique neuroplastic period in adult life. This longitudinal study tracked brain
cortical changes during the peripartum period and explored how the type of childbirth affects …

Beyond sex differences: short-and long-term effects of pregnancy on the brain

TA Puri, JE Richard, LAM Galea - Trends in Neurosciences, 2023 - cell.com
Growing attention has been directed to the inclusion of females in neuroscience studies, and
to the importance of studying sex as a biological variable. However, how female-specific …