[HTML][HTML] Mechanistic correlation between mitochondrial permeability transition pores and mitochondrial ATP dependent potassium channels in ischemia reperfusion

R Behera, V Sharma, AK Grewal, A Kumar… - Biomedicine & …, 2023 - Elsevier
Mitochondrial dysfunction is one of the fundamental causes of ischemia reperfusion (I/R)
damage. I/R refers to the paradoxical progression of cellular dysfunction and death that …

DNA damage response signaling: A common link between cancer and cardiovascular diseases

S Nikfarjam, KK Singh - Cancer medicine, 2023 - Wiley Online Library
DNA damage response (DDR) signaling ensures genomic and proteomic homeostasis to
maintain a healthy genome. Dysregulation either in the form of down‐or upregulation in the …

Quercetin modulates AMPK/SIRT1/NF‑κB signaling to inhibit inflammatory/oxidative stress responses in diabetic high fat diet‑induced atherosclerosis in the rat carotid …

F Zhang, J Feng, J Zhang… - Experimental and …, 2020 - spandidos-publications.com
Inflammation and oxidative stress serve interrelated roles in the development of
atherosclerosis and other vascular diseases. Quercetin has been previously reported to …

Resveratrol increase myocardial Nrf2 expression in type 2 diabetic rats and alleviate myocardial ischemia/reperfusion injury (MIRI)

G Xu, X Zhao, J Fu, X Wang - Annals of palliative medicine, 2019 - apm.amegroups.org
Background: Oxidative stress is one of the main factors that increases reperfusion injury in
the diabetic heart. Resveratrol could decrease oxidation and promote antioxidant factor …

Role of oxidative DNA damage and repair in atrial fibrillation and ischemic heart disease

L Hu, Z Wang, C Carmone, J Keijer… - International journal of …, 2021 - mdpi.com
Atrial fibrillation (AF) and ischemic heart disease (IHD) represent the two most common
clinical cardiac diseases, characterized by angina, arrhythmia, myocardial damage, and …

An updated insight into molecular mechanism of hydrogen sulfide in cardiomyopathy and myocardial ischemia/reperfusion injury under diabetes

HJ Sun, ZY Wu, XW Nie, XY Wang… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular diseases are the most common complications of diabetes, and diabetic
cardiomyopathy is a major cause of people death in diabetes. Molecular, transcriptional …

Mechanisms and Therapeutic Strategies for Myocardial Ischemia-Reperfusion Injury in Diabetic States

J Xue, J Zhuang, X Wang, T Meng, J Wu… - ACS Pharmacology & …, 2024 - ACS Publications
In patients with myocardial infarction, one of the complications that may occur after
revascularization is myocardial ischemia-reperfusion injury (IRI), characterized by a …

[HTML][HTML] Cardioprotective effects of melatonin: Focusing on its roles against diabetic cardiomyopathy

YJ Song, CB Zhong, W Wu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Melatonin is a pineal-produced indole known for its anti-aging, antiapoptotic and antioxidant
properties. In past decades, the protective potentials of melatonin for cardiovascular …

Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions

L Hosseini, MS Vafaee, J Mahmoudi, R Badalzadeh - Biogerontology, 2019 - Springer
Nicotinamide adenine dinucleotide (NAD+) has been described as central coenzyme of
redox reactions and is a key regulator of stress resistance and longevity. Aging is a …

Diabetes, fasting blood glucose and the efficacy of remote ischaemic conditioning: a secondary analysis of the RICAMIS trial

YN Zhang, YJ Dai, Y Cui, Q Wu… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To investigate whether diabetes and fasting blood glucose (FBG) levels affect the
efficacy of remote ischaemic conditioning (RIC) using the database included in the Remote …