Synthesis of cyclopentitols by ring-closing approaches

VB Kurteva, CAM Afonso - Chemical reviews, 2009 - ACS Publications
Considerable effort has been devoted in the past decades to the development of new
methods for the construction of five-membered carbocycles, since they play a fundamental …

Chemical approaches to carbocyclic nucleosides

AC Ojeda‐Porras, V Roy… - The Chemical Record, 2022 - Wiley Online Library
Nucleoside analogues are at the forefront of antiviral therapy for last decades. To circumvent
some of their limitations, based on their metabolism, and in order to improve their anti‐viral …

Solvothermal alcoholysis routes for recycling polylactide waste as lactic acid esters

R Petrus, D Bykowski, P Sobota - ACS Catalysis, 2016 - ACS Publications
In this work, we investigated the possible use of polylactide (PLA), a biodegradable polymer
obtained from renewable biofeedstock, to produce a range of industrially useful lactic acid …

A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations

E dos Santos Pinheiro, OAC Antunes, JMD Fortunak - Antiviral Research, 2008 - Elsevier
It has been roughly 25 years since the threat posed by human immunodeficiency virus type
1 (HIV-1) became widely known. The cumulative death toll from HIV/AIDS is now greater …

Chemoselective alcoholysis of lactide mediated by a magnesium catalyst: an efficient route to alkyl lactyllactate

A Grala, J Ejfler, LB Jerzykiewicz, P Sobota - Dalton Transactions, 2011 - pubs.rsc.org
Alkyl-(S, S)-O-lactyllactate was prepared by chemoselective alcoholysis of lactide LA
mediated by a magnesium catalyst. When ROH reacted with LA it yielded the ring-opened …

Base-catalyzed domino cyclization of acetylenes with ketones to functionalized cyclopentenes

EY Schmidt, BA Trofimov, IA Bidusenko… - Organic …, 2014 - ACS Publications
Acetylene reacts with methylaryl (hetaryl) ketones in the presence of 6.5 mol% KOH in
DMSO to give diastereoselectively in single operationally functionalized cyclopentenes. This …

Two classes of heterocycles—6, 8‐dioxabicyclo [3.2. 1] octanes and cyclopentenols from the same reagents: A quantum‐chemical comparison of mechanism

NM Vitkovskaya, VB Orel, VB Kobychev… - … Journal of Quantum …, 2018 - Wiley Online Library
Most of the strategies for the synthesis of 6, 8‐dioxabicyclo [3.2. 1] octanes (BCO) and
cyclopentenols (CP), which show high biological and pharmaceutical activity, are multistage …

[图书][B] Organic Reactions, Volume 100

SE Denmark - 2019 - books.google.com
Written by a" who is who" of leading organic chemists, this anniversary volume represent the
Organic Reactions editors' choice of the most important, ground-breaking and versatile …

Olefin Ring‐Closing Metathesis

L Yet - Organic Reactions, 2004 - Wiley Online Library
The olefin ring‐closing metathesis reaction catalyzed by ruthenium and molybdenum
complexes has been employed in the syntheses of carbocycles, heterocycles …

Synthesis of alkyl (R)-lactates and alkyl (S, S)-O-lactyllactates by alcoholysis of rac-lactide using Novozym 435

NY Jeon, SJ Ko, K Won, HY Kang, BT Kim, YS Lee… - Tetrahedron letters, 2006 - Elsevier
Enzymatic alcoholysis of rac-lactide for kinetic resolution was carried out in organic solvents.
Effects of organic solvent, reaction temperature, and alcohol as a nucleophile were also …