Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …

Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …

Microbes are known to colonize surfaces and form biofilms. These biofilms are communities
of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and …

Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Building and maintaining a homeostatic relationship between a host and its colonizing
microbiota entails ongoing complex interactions between the host and the microorganisms …

Systemic lupus erythematosus (SLE) is a severe and incurable autoimmune disease
characterized by chronic activation of plasmacytoid dendritic cells (pDCs) and production of …

Mammals and their intestinal microbiota peacefully coexist in a mutualistic relationship.
Commensal bacteria play an active role in shaping and modulating physiological processes …

Commensal bacteria are known to inhibit pathogen colonization; however, complex host–
microbe and microbe–microbe interactions have made it difficult to gain a detailed …