Abstract Forkhead Box M1 (FOXM1) is a bona fide oncofoetal transcription factor, which
orchestrates complex temporal and spatial gene expression throughout embryonic and …

Factors released from glioma-associated microglia/macrophages (GAMs) play a crucial role
in glioblastoma multiforme (GBM) progression. Here, we study the importance of CCL18, a …

Lower-grade glioma (LGG) is characterized by genetic and transcriptional heterogeneity,
and a dismal prognosis. Iron metabolism is considered central for glioma tumorigenesis …

Objective: Atherosclerosis is closely associated with ischemic stroke, and long noncoding
RNA-H19 (lncRNA-H19) might be a potential target for treating atherosclerosis. The present …

Background Spinal cord injury (SCI) results in fatal damage and currently has no effective
treatment. The pathological mechanisms of SCI remain unclear. In this study, genome-wide …

Previous studies have indicated that males are at a higher risk of developing hepatocellular
carcinoma (HCC) compared with females. Identifying the factors that cause this gender …

Osteoporosis is a global disease caused by abnormal overactivation of osteoclasts. The
acidic environment in sealing zone of osteoclasts with H+ pumped from cytoplasm is critical …

Background Recent evidence suggests that the aberrant activation of Hedgehog (Hh)
signaling by Gli transcription factors is characteristic of a variety of aggressive human …

Tartrate-resistant acid phosphatase 5 (TRAP/ACP5) has been shown to involve the
development and prognosis of multiple tumors in previous studies; however, the mechanism …

Background To understand the involvement of structural maintenance of chromosome 4
(SMC4) in the development and progression of hepatocellular carcinoma (HCC). Methods …