Cerebral palsy (CP) is a complex multifactorial disorder, affecting approximately 2.5–3/1000
live term births, and up to 22/1000 prematurely born babies. CP results from injury to the …

Extremely low-gestational-age newborns have a prominently increased risk of brain
dysfunctions attributed to white-matter damage, which is thought to result from the …

The premature infant is at increased risk of cerebral white matter injury. Melatonin is
neuroprotective in adult models of focal cerebral ischemia and attenuates ibotenate-induced …

Fetal/neonatal brain injury is an important cause of neurological disability. Hypoxia‐
ischemia and excitotoxicity are considered important insults, and, in spite of their acute …

Increasingly distinct patterns of focal ischemic injury in the fetal and perinatal brain are
recognized. Improved classification has afforded advances in risk factor identification …

CD4+ T cell subsets play an important role in the adaptive immune response in human
autoimmune diseases and in animal models of autoimmunity. In recent years, our …

Recent research has pointed to the developing immune system as a remarkably sensitive
toxicologic target for environmental chemicals and drugs. In fact, the perinatal period before …

Autism spectrum disorder (ASD) gradually develops predominantly neurodevelopmental
disorders, which are socially diagnosed in early childhood. Though the etiopathology of …

Autism spectrum disorder (ASD) is a common neurodevelopmental illness characterized by
abnormal social interactions, communication difficulties, and repetitive and limited behaviors …

Background Perinatal brain injury is complex and associated with both inflammation and
hypoxia-ischaemia (HI). In adult inflammatory brain injury models, therapies to increase …