The role of engram cells in the systems consolidation of memory

S Tonegawa, MD Morrissey, T Kitamura - Nature Reviews …, 2018 - nature.com
What happens to memories as days, weeks and years go by has long been a fundamental
question in neuroscience and psychology. For decades, researchers have attempted to …

Viral tools for neuroscience

AR Nectow, EJ Nestler - Nature Reviews Neuroscience, 2020 - nature.com
Recombinant viruses are the workhorse of modern neuroscience. Whether one would like to
understand a neuron's morphology, natural activity patterns, molecular composition …

[HTML][HTML] Multimodal analysis of cell types in a hypothalamic node controlling social behavior

DW Kim, Z Yao, LT Graybuck, TK Kim, TN Nguyen… - Cell, 2019 - cell.com
The ventrolateral subdivision of the ventromedial hypothalamus (VMHvl) contains∼ 4,000
neurons that project to multiple targets and control innate social behaviors including …

The whisking oscillator circuit

J Takatoh, V Prevosto, PM Thompson, J Lu, L Chung… - Nature, 2022 - nature.com
Central oscillators are primordial neural circuits that generate and control rhythmic
movements,. Mechanistic understanding of these circuits requires genetic identification of …

Divergent neural pathways emanating from the lateral parabrachial nucleus mediate distinct components of the pain response

MC Chiang, EK Nguyen, M Canto-Bustos, AE Papale… - Neuron, 2020 - cell.com
The lateral parabrachial nucleus (lPBN) is a major target of spinal projection neurons
conveying nociceptive input into supraspinal structures. However, the functional role of …

Understanding the physical basis of memory: Molecular mechanisms of the engram

C Ortega-de San Luis, TJ Ryan - Journal of Biological Chemistry, 2022 - ASBMB
Memory, defined as the storage and use of learned information in the brain, is necessary to
modulate behavior and critical for animals to adapt to their environments and survive …

Fighting females: neural and behavioral consequences of social defeat stress in female mice

EL Newman, HE Covington III, J Suh, MB Bicakci… - Biological …, 2019 - Elsevier
Background Despite the twofold higher prevalence of major depressive and posttraumatic
stress disorders in women compared with men, most clinical and preclinical studies have …

A systems neuroscience approach to migraine

KC Brennan, D Pietrobon - Neuron, 2018 - cell.com
A Systems Neuroscience Approach to Migraine: Neuron Skip to Main Content Advertisement
Neuron This journal offers authors two options (open access or subscription) to publish …

General anesthetics activate a potent central pain-suppression circuit in the amygdala

T Hua, B Chen, D Lu, K Sakurai, S Zhao, BX Han… - Nature …, 2020 - nature.com
General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss
of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA …

Medial preoptic area in mice is capable of mediating sexually dimorphic behaviors regardless of gender

YC Wei, SR Wang, ZL Jiao, W Zhang, JK Lin… - Nature …, 2018 - nature.com
The medial preoptic area (mPOA) differs between males and females in nearly all species
examined to date, including humans. Here, using fiber photometry recordings of Ca2+ …