Aging is associated with a progressive decline in cardiovascular structure and function.
Accumulating evidence links cardiovascular aging to epigenetic alterations encompassing a …

Macrophages are pivotal in the initiation and development of atherosclerotic cardiovascular
diseases. Recent studies have reinforced the importance of mitochondria in metabolic and …

Atherosclerosis is a disorder occurring in the large arteries and the primary cause of heart
diseases. Accumulating evidence has implicated long non-coding RNAs (lncRNAs) in …

Background Atherosclerosis severity-independent alterations in DNA methylation, a
reversible and highly regulated DNA modification, have been detected in aortic atheromas …

Atheromatous disease is the first cause of death and dependency in developed countries
and carotid artery atherosclerosis is one of the main causes of severe ischaemic strokes …

In the study of longevity, increasing importance is being placed on the concept of healthy
aging rather than considering the total number of years lived. Although the concept of …

Epigenetic mechanisms of gene regulation in context of cardiovascular diseases are of
considerable interest. So far, our current knowledge of the DNA methylation profiles for …

Chronic, noncommunicable, and inflammation-associated diseases remain the largest
cause of morbidity and mortality globally and within the United States. This is mainly due to …

Abstract Genome-wide Illumina InfiniumMethylation 450 K DNA methylation analysis was
performed on blood samples from clinical atherosclerosis patients (n= 8) and healthy donors …

Atherosclerosis is associated with multiple genetic and modifiable risk factors. There is an
increasing body of evidences to indicate that epigenetic mechanisms also play an essential …