Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer

N Li, X Zhang, J Zhou, W Li, X Shu, Y Wu… - Advanced Drug Delivery …, 2022 - Elsevier
A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …

Applications of nanobiomaterials in the therapy and imaging of acute liver failure

Y Jin, H Wang, K Yi, S Lv, H Hu, M Li, Y Tao - Nano-micro letters, 2021 - Springer
Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …

Open-source image reconstruction of super-resolution structured illumination microscopy data in ImageJ

M Müller, V Mönkemöller, S Hennig, W Hübner… - Nature …, 2016 - nature.com
Super-resolved structured illumination microscopy (SR-SIM) is an important tool for
fluorescence microscopy. SR-SIM microscopes perform multiple image acquisitions with …

Video-rate multi-color structured illumination microscopy with simultaneous real-time reconstruction

A Markwirth, M Lachetta, V Mönkemöller… - Nature …, 2019 - nature.com
Super-resolved structured illumination microscopy (SR-SIM) is among the fastest
fluorescence microscopy techniques capable of surpassing the optical diffraction limit …

Liver sinusoidal endothelial cells

KK Sørensen, J Simon‐Santamaria… - Comprehensive …, 2011 - Wiley Online Library
The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …

Chip-based wide field-of-view nanoscopy

R Diekmann, ØI Helle, CI Øie, P McCourt, TR Huser… - Nature …, 2017 - nature.com
Present optical nanoscopy techniques use a complex microscope for imaging and a simple
glass slide to hold the sample. Here, we demonstrate the inverse: the use of a complex, but …

Diagnostic imaging and therapeutic application of nanoparticles targeting the liver

H Wang, CA Thorling, X Liang, KR Bridle… - Journal of Materials …, 2015 - pubs.rsc.org
Liver diseases, particularly viral hepatitis, cirrhosis and hepatocellular carcinoma, are
common in clinical practice with high morbidity and mortality worldwide. Many substances …

The unique structural and functional characteristics of glomerular endothelial cell fenestrations and their potential as a therapeutic target in kidney disease

NC Finch, CR Neal, GI Welsh… - American Journal of …, 2023 - journals.physiology.org
Glomerular endothelial cell (GEnC) fenestrations are a critical component of the glomerular
filtration barrier. Their unique nondiaphragmed structure is key to their function in glomerular …

Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles

L Andronov, M Han, Y Zhu, A Balaji, AR Roy… - Nature …, 2024 - nature.com
The SARS-CoV-2 viral infection transforms host cells and produces special organelles in
many ways, and we focus on the replication organelles, the sites of replication of viral …

Nanoscopy of bacterial cells immobilized by holographic optical tweezers

R Diekmann, DL Wolfson, C Spahn… - Nature …, 2016 - nature.com
Imaging non-adherent cells by super-resolution far-field fluorescence microscopy is
currently not possible because of their rapid movement while in suspension. Holographic …