[HTML][HTML] Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders

BA Bhat, A Almilaibary, RA Mir, BM Aljarallah… - Frontiers in …, 2022 - frontiersin.org
The current scientific community is facing a daunting challenge to unravel reliable natural
compounds with realistic potential to treat neurological disorders such as Alzheimer's …

[HTML][HTML] Progress and impact of Latin American natural product databases

A Gómez-García, JL Medina-Franco - Biomolecules, 2022 - mdpi.com
Natural products (NPs) are a rich source of structurally novel molecules, and the chemical
space they encompass is far from being fully explored. Over history, NPs have represented a …

[HTML][HTML] Multicomponent reaction-assisted drug discovery: A time-and cost-effective green approach speeding up identification and optimization of anticancer drugs

G Graziano, A Stefanachi, M Contino… - International Journal of …, 2023 - mdpi.com
Multicomponent reactions (MCRs) have emerged as a powerful strategy in synthetic organic
chemistry due to their widespread applications in drug discovery and development. MCRs …

[HTML][HTML] Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects

L Pereira, A Valado - Life, 2023 - mdpi.com
Diabetes poses a significant global health challenge, necessitating innovative therapeutic
strategies. Natural products and their derivatives have emerged as promising candidates for …

Clinical evidence construction of East Asian herbal medicine for inflammatory pain in rheumatoid arthritis based on integrative data mining approach

HG Jo, J Seo, D Lee - Pharmacological Research, 2022 - Elsevier
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to a
significant social burden. East Asian herbal medicine (EAHM) has long been used to treat …

[HTML][HTML] Anthocyanins as Immunomodulatory Dietary Supplements: A Nutraceutical Perspective and Micro-/Nano-Strategies for Enhanced Bioavailability

TP Ijinu, LF De Lellis, S Shanmugarama… - Nutrients, 2023 - mdpi.com
Anthocyanins (ACNs) have attracted considerable attention for their potential to modulate
the immune system. Research has revealed their antioxidant and anti-inflammatory …

Triterpenoids as reactive oxygen species modulators of cell fate

T Ling, L Boyd, F Rivas - Chemical Research in Toxicology, 2022 - ACS Publications
The triterpenoid natural products have played an important role in understanding
mechanistic models of human diseases. These natural products are diverse, but many have …

[HTML][HTML] Identification of triterpenoid saponin inhibitors of interleukin (IL)-33 signaling from the roots of Astragalus membranaceus

LB Vinh, YK Han, SY Park, YJ Kim, NV Phong… - Journal of Functional …, 2023 - Elsevier
Abstract Interleukin-33 (IL-33) is a cytokine produced by epithelial cells that plays a key role
in immune-mediated diseases, such as asthma, atopic dermatitis, and rheumatoid arthritis …

Immunomodulatory compounds from the sea: From the origins to a modern marine pharmacopoeia

EA Cutolo, R Campitiello, R Caferri, VF Pagliuca, J Li… - Marine Drugs, 2024 - mdpi.com
From sea shores to the abysses of the deep ocean, marine ecosystems have provided
humanity with valuable medicinal resources. The use of marine organisms is discussed in …

[HTML][HTML] Efficacy and key materials of East Asian herbal medicine combined with conventional medicine on inflammatory skin lesion in patients with psoriasis vulgaris …

HG Jo, H Kim, E Baek, D Lee, JH Hwang - Pharmaceuticals, 2023 - mdpi.com
Psoriasis is a chronic inflammatory disease that places a great burden on both individuals
and society. The use of East Asian herbal medicine (EAHM) in combination with …