Erdosteine was introduced in the market as a mucolytic agent for chronic pulmonary
diseases more than 10 years ago. The drug contains two blocked sulphydryl groups one of …

Methotrexate (MTX), a folic acid antagonist, is widely used as a cytotoxic chemotherapeutic
agent. MTX-associated neurotoxicity is an important clinical problem. The aim of this study …

As an effective compound found mainly in the honeybee product propolis, caffeic acid
phenethyl ester (CAPE) has been commonly utilized as a medicine and remedial agent, in a …

Purpose: This study intended to examine the effect of caffeic acid phenethyl ester (CAPE) on
isoniazid (INH) and/or ethambutol (ETM)-induced retina and optic nerve toxicity in a rat …

Background Curcumin, an active ingredient of turmeric with antioxidant and anti-
inflammatory properties has recently been reported to have anticonvulsant effects in several …

Background. The aim of the study was to analyse the effect of caffeic acid phenethyl ester
(CAPE) on fluoxetine‐induced hepatotoxicity in rats. Materials and Methods. Group I served …

Isoniazid (INH) still remains a first-line drug both for treatment and prophylaxis of
tuberculosis, but various organs toxicity frequently develops in patients receiving this drug …

Methods: A total of 6 mice received JB (10–50 mg/kg, PO), pyridoxine (300 mg/kg),
diazepam (5 mg/kg), or distilled water (10 mL/kg) 30 minutes prior to the induction of SE with …

The aim of this experimental study was to investigate the possible role of nitric oxide (NO)
and the activities of adenosine deaminase (ADA) and xanthine oxidase (XO) in the …

This study aimed at investigating the effects of chronic mild stress on DNA damage, NMDA
receptor subunits and glutamate transport levels in the brains of rats with an anxious …