Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the
global health care industry. While a small minority of joint arthroplasties will become …

Objectives The diagnosis of periprosthetic joint infection (PJI) is difficult and requires a
battery of tests and clinical findings. The purpose of this review is to summarize all current …

Diagnosing Periprosthetic Joint Infection: Has the Era of th... : Clinical Orthopaedics and Related
Research® Diagnosing Periprosthetic Joint Infection: Has the Era of the Biomarker Arrived …

Background For the diagnosis of prosthetic joint infection, real evidence-based guidelines to
aid clinicians in choosing the most accurate diagnostic strategy are lacking. Aim and …

Background: The diagnosis of periprosthetic joint infection remains a challenge. The
purpose of this study was to evaluate the combined measurement of the levels of two …

Background Synovial fluid biomarkers have demonstrated diagnostic accuracy surpassing
the currently used diagnostic tests for periprosthetic joint infection (PJI). Questions/purposes …

Background The purpose of this study was to test the accuracy of a single synovial fluid
biomarker, α-defensin, in diagnosing periprosthetic joint infection in revision total hip and …

Background The volume of joint replacement surgery has risen steadily in recent years,
because the population is aging and increasingly wishes to preserve a high functional status …

The preoperative differentiation between septic and aseptic loosening after total hip or knee
arthroplasty is essential for successful therapy and relies in part on biomarkers. The …

Background: Bacterial resistance to available antibiotics has resulted in enhanced efforts at
antibiotic stewardship but also has led to investigation into alternative methods for managing …