An overview of albumin and alpha-1-acid glycoprotein main characteristics: highlighting the roles of amino acids in binding kinetics and molecular interactions

M Bteich - Heliyon, 2019 - cell.com
Although Albumin (ALB) and alpha-1-acid glycoprotein (AGP) have distinctive structural and
functional characteristics, they both play a key role in binding a large variety of endogenous …

A mechanistic insight into protein-ligand interaction, folding, misfolding, aggregation and inhibition of protein aggregates: An overview

TI Chandel, M Zaman, MV Khan, M Ali… - International journal of …, 2018 - Elsevier
This review article summarises the possible mechanisms of the protein-ligand interaction,
folding, misfolding, aggregation and inhibition of protein aggregates. Under certain stressed …

Probing the interaction of Rivastigmine Tartrate, an important Alzheimer's drug, with serum albumin: Attempting treatment of Alzheimer's disease

A Shamsi, T Mohammad, S Anwar, MF Alajmi… - International journal of …, 2020 - Elsevier
The present study was aimed at investigating the binding between an important drug of
Alzheimer's therapy, Rivastigmine tartrate (RT), with Bovine serum albumin (BSA). BSA is a …

A comprehensive spectroscopic and computational investigation to probe the interaction of antineoplastic drug nordihydroguaiaretic acid with serum albumins

S Nusrat, MK Siddiqi, M Zaman, N Zaidi, MR Ajmal… - PLoS …, 2016 - journals.plos.org
Exogenous drugs that are used as antidote against chemotheray, inflammation or viral
infection, gets absorbed and interacts reversibly to the major serum transport protein ie …

Curcumin complexed with graphene derivative for breast cancer therapy

D De, CK Das, D Mandal, M Mandal… - ACS Applied Bio …, 2020 - ACS Publications
In recent years, graphene-based materials complexed with drugs have been developed for
application in cancer therapy, aimed at gaining synergistic effect. Here, we have prepared …

Inhibition of α-glucosidase activity and non-enzymatic glycation by tannic acid: Inhibitory activity and molecular mechanism

Q Huang, WM Chai, ZY Ma, C Ou-Yang, QM Wei… - International journal of …, 2019 - Elsevier
The inhibition of α-glucosidase and glycation is considered as an effective approach for the
treatment of type 2 diabetes. In this study, multispectroscopic and molecular docking …

Probing the interaction of anticancer drug temsirolimus with human serum albumin: Molecular docking and spectroscopic insight

A Shamsi, A Ahmed, B Bano - Journal of Biomolecular Structure …, 2018 - Taylor & Francis
The binding interaction between temsirolimus, an important antirenal cancer drug, and HSA,
an important carrier protein was scrutinized making use of UV and fluorescence …

Anti-amyloidogenic behavior and interaction of diallylsulfide with human serum albumin

MK Siddiqi, P Alam, SK Chaturvedi, RH Khan - International journal of …, 2016 - Elsevier
In this work, binding of garlic component-Diallysulfide (DAS) with major human blood
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …

Investigation on the anti-α-glucosidase mechanism of aspergillus triazolate A from Oxalis corniculate L.

Q Feng, W Yang, X Ma, Z Peng, G Wang - International Journal of …, 2024 - Elsevier
Diabetes mellitus characterized by abnormal glucose concentration is a metabolic disease.
α-Glu inhibitors from natural sources are a good choice for searching for high-efficiency and …

Attenuation of amyloid fibrillation in presence of Warfarin: a biophysical investigation

MK Siddiqi, P Alam, SK Chaturvedi, S Nusrat… - International journal of …, 2017 - Elsevier
Protein misfolding and aggregation are associated with more than twenty diseases, such as
neurodegenerative diseases. The amyloid oligomers and fibrils may induce cell membrane …