Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …

Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation,
and survival of sympathetic and sensory afferent neurons during development. A substantial …

The physiological role of the neurotrophin nerve growth factor (NGF) has been
characterized, since its discovery in the 1950s, first in the sensory and autonomic nervous …

Neurotrophins and their receptors modulate multiple signalling pathways to regulate
neuronal survival and to maintain axonal and dendritic networks and synaptic plasticity …

Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor
(BDNF) play multiple roles in different settings including neuronal development, function and …

Despite the devastating effect of suicide on numerous lives, there is still a lack of knowledge
concerning its neurochemical aspects. There is increasing evidence that brain-derived …

Hereditary sensory and autonomic neuropathies (HSANs) are a clinically and genetically
heterogeneous group of disorders of the PNS. Progressive degeneration, predominantly of …

Background/Aims: Degeneration of cholinergic neurons in the basal forebrain correlates
with cognitive decline in patients with Alzheimer's disease (AD). Targeted delivery of …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
amyloid-β peptide misfolding and aggregation. Neurotrophic factors, such as nerve growth …

Messenger RNA (mRNA) carries genetic instructions to the cell machinery for the transient
production of antigens or therapeutic proteins and shows enormous potential in vaccine …