Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives

S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular Plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …

Integrative omics approaches for biosynthetic pathway discovery in plants

KS Singh, JJJ van der Hooft, SCM van Wees… - Natural Product …, 2022 - pubs.rsc.org
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …

Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking

Z Zhou, M Luo, H Zhang, Y Yin, Y Cai, ZJ Zhu - Nature Communications, 2022 - nature.com
Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …

Plant and microbial sciences as key drivers in the development of metabolomics research

A Aharoni, R Goodacre… - Proceedings of the …, 2023 - National Acad Sciences
This year marks the 25th anniversary of the coinage of the term metabolome [SG Oliver et
al., Trends Biotech. 16, 373–378 (1998)]. As the field rapidly advances, it is important to take …

Recent advances in proteomics and metabolomics in plants

S Yan, R Bhawal, Z Yin, TW Thannhauser… - Molecular Horticulture, 2022 - Springer
Over the past decade, systems biology and plant-omics have increasingly become the main
stream in plant biology research. New developments in mass spectrometry and …

Machine learning-assisted structure annotation of natural products based on MS and NMR data

G Hu, M Qiu - Natural Product Reports, 2023 - pubs.rsc.org
Covering: up to March 2023Machine learning (ML) has emerged as a popular tool for
analyzing the structures of natural products (NPs). This review presents a summary of the …

Bioinformatics in bioscience and bioengineering: recent advances, applications, and perspectives

K Uesaka, H Oka, R Kato, K Kanie, T Kojima… - Journal of bioscience …, 2022 - Elsevier
Recent advances have led to the emergence of highly comprehensive and analytical
approaches, such as omics analysis and high-resolution, time-resolved bioimaging analysis …

Capturing the microbial volatilome: an oft overlooked'ome'

LK Meredith, MM Tfaily - Trends in Microbiology, 2022 - cell.com
Among the diverse metabolites produced by microbial communities, some are volatile.
Volatile organic compounds (VOCs) are vigorously cycled by microbes as metabolic …

Metabolomics and Genomics Enable the Discovery of a New Class of Nonribosomal Peptidic Metallophores from a Marine Micromonospora

Q Wu, BA Bell, JX Yan, MG Chevrette… - Journal of the …, 2022 - ACS Publications
Although microbial genomes harbor an abundance of biosynthetic gene clusters, there
remain substantial technological gaps that impair the direct correlation of newly discovered …

Stable isotope-resolved metabolomics based on mass spectrometry: Methods and their applications

D Yu, L Zhou, X Liu, G Xu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The introduction of stable isotope labeling (SIL) technology into metabolomics can provide
insight into the" dynamic" metabolic regulation in organisms and has recently become a …