Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary

C Varilla, M Marcone, L Paiva, J Baptista - Foods, 2021 - mdpi.com
Bromelain is a complex combination of multiple endopeptidases of thiol and other
compounds derived from the pineapple fruit, stem and/or root. Fruit bromelain and stem …

Potential role of bromelain in clinical and therapeutic applications

V Rathnavelu, NB Alitheen, S Sohila… - Biomedical …, 2016 - spandidos-publications.com
Pineapple has been used as part of traditional folk medicine since ancient times and it
continues to be present in various herbal preparations. Bromelain is a complex mixture of …

Valorisation of pineapple wastes for food and therapeutic applications

S Banerjee, V Ranganathan, A Patti, A Arora - Trends in food science & …, 2018 - Elsevier
Background Fruit and vegetable processing industries account for the largest segment of
food waste which is produced worldwide. The disposal of this waste requires a huge capital …

[PDF][PDF] Natural products and anti-inflammatory activity.

G Yuan, ML Wahlqvist, G He, M Yang… - Asia Pacific journal of …, 2006 - academia.edu
The aim of this review paper was to summarise some commonly available natural products
and their antiinflammatory activity. We have collected data from MEDLINE, Current Contents …

Bromelain: A review of its mechanisms, pharmacological effects and potential applications

V Kumar, B Mangla, S Javed, W Ahsan, P Kumar… - Food & function, 2023 - pubs.rsc.org
The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …

[HTML][HTML] Bromelain as a treatment for osteoarthritis: a review of clinical studies

S Brien, G Lewith, A Walker, SM Hicks… - Evidence-based …, 2004 - ncbi.nlm.nih.gov
Bromelain, an extract from the pineapple plant, has been demonstrated to show anti-
inflammatory and analgesic properties and may provide a safer alternative or adjunctive …

Production of plant proteases in vivo and in vitro—a review

N Gonzalez-Rabade, JA Badillo-Corona… - Biotechnology …, 2011 - Elsevier
In the latest two decades, the interest received by plant proteases has increased
significantly. Plant enzymes such as proteases are widely used in medicine and the food …

Bromelain: Methods of extraction, purification and therapeutic applications

Z Manzoor, A Nawaz, H Mukhtar, I Haq - Brazilian Archives of Biology …, 2016 - SciELO Brasil
Bromelain is a concoction of sulfhydryl proteolytic enzymes. Depending upon the site of
extraction it can be regarded as either stem bromelain (SBM)(EC 3.4. 22.32) or fruit …

Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo …

OW Majid, BA Al-Mashhadani - Journal of Oral and Maxillofacial Surgery, 2014 - Elsevier
Purpose The purpose of the present study was to compare the effect of oral bromelain (4×
250 mg) versus oral diclofenac sodium (4× 25 mg) on pain, swelling, trismus, and quality of …