The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Idiopathic pulmonary fibrosis is a progressive and usually fatal lung disease characterized
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions
worldwide with a high mortality rate due to a lack of definitive treatment. Despite having a …

Abstract In 1977, Mason and Williams developed the concept of the alveolar epithelial type II
(AE2) cell as a defender of the alveolus. It is well known that AE2 cells synthesise, secrete …

Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease of
unknown origin whose incidence has been increasing over the latest decade partly as a …

The role of apoptosis in acute lung injury : Critical Care Medicine The role of apoptosis in
acute lung injury : Critical Care Medicine SCCM Pediatric Critical Care Medicine Critical Care …

The synovial tissue is an immunologically challenging environment where, under
homeostatic conditions, highly specialized subsets of immune-regulatory macrophages and …

Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Derangement in pulmonary surfactant or its components and alveolar collapse are common
findings in idiopathic pulmonary fibrosis (IPF). Surfactant proteins play important roles in …

Apoptosis is a process of controlled cellular death whereby the activation of specific death-
signaling pathways leads to deletion of cells from tissue. The importance of apoptosis …