The survival mechanisms of thermophiles at high temperatures: an angle of omics

Q Wang, Z Cen, J Zhao - Physiology, 2015 - journals.physiology.org
Thermophiles are referred to as microorganisms with optimal growth temperatures of> 60°
C. Over the past few years, a number of studies have been conducted regarding …

Ab initio gene identification in metagenomic sequences

W Zhu, A Lomsadze, M Borodovsky - Nucleic acids research, 2010 - academic.oup.com
We describe an algorithm for gene identification in DNA sequences derived from shotgun
sequencing of microbial communities. Accurate ab initio gene prediction in a short …

Microbial lifestyle and genome signatures

C Dutta, S Paul - Current genomics, 2012 - ingentaconnect.com
Microbes are known for their unique ability to adapt to varying lifestyle and environment,
even to the extreme or adverse ones. The genomic architecture of a microbe may bear the …

A site-and time-heterogeneous model of amino acid replacement

S Blanquart, N Lartillot - Molecular biology and evolution, 2008 - academic.oup.com
We combined the category (CAT) mixture model (Lartillot N, Philippe H. 2004) and the
nonstationary break point (BP) model (Blanquart S, Lartillot N. 2006) into a new model, CAT …

Genomics of an extreme psychrophile, Psychromonas ingrahamii

M Riley, JT Staley, A Danchin, TZ Wang, TS Brettin… - BMC genomics, 2008 - Springer
Background The genome sequence of the sea-ice bacterium Psychromonas ingrahamii 37,
which grows exponentially at-12C, may reveal features that help to explain how this extreme …

Environment and taxonomy shape the genomic signature of prokaryotic extremophiles

PM Arias, J Butler, GS Randhawa, MPM Soltysiak… - Scientific Reports, 2023 - nature.com
This study provides comprehensive quantitative evidence suggesting that adaptations to
extreme temperatures and pH imprint a discernible environmental component in the …

[HTML][HTML] Genomics of prokaryotic extremophiles to unfold the mystery of survival in extreme environments

R Salwan, V Sharma - Microbiological research, 2022 - Elsevier
The organisms surviving in extreme environments deploy system support including self-
protection, and energy distribution to counter extreme environmental stresses. The …

Codon usage bias in yeasts and its correlation with gene expression, growth temperature, and protein structure

M Baeza, D Sepulveda, V Cifuentes… - Frontiers in …, 2024 - frontiersin.org
Codon usage bias (CUB) has been described in viruses, prokaryotes, and eukaryotes and
has been linked to several cellular and environmental factors, such as the organism's growth …

Neutralism versus selectionism: Chargaff's second parity rule, revisited

DR Forsdyke - Genetica, 2021 - Springer
Of Chargaff's four" rules" on DNA base frequencies, the functional interpretation of his
second parity rule (PR2) is the most contentious. Thermophile base compositions (GC%) …

[HTML][HTML] A large-scale analysis of codon usage bias in 4868 bacterial genomes shows association of codon adaptation index with GC content, protein functional …

A Masłowska-Górnicz, MRM van den Bosch… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Multiple synonymous codons code for the same amino acid, resulting in the degeneracy of
the genetic code and in the preferred used of some codons called codon bias usage (CBU) …