Cellular and molecular mechanisms of kidney fibrosis

S Djudjaj, P Boor - Molecular aspects of medicine, 2019 - Elsevier
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …

Cellular and molecular mechanisms of renal fibrosis

Y Liu - Nature Reviews Nephrology, 2011 - nature.com
Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

Renal fibrosis: novel insights into mechanisms and therapeutic targets

P Boor, T Ostendorf, J Floege - Nature Reviews Nephrology, 2010 - nature.com
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …

Renal interstitial fibrosis: mechanisms and evaluation

AB Farris, RB Colvin - Current opinion in nephrology and …, 2012 - journals.lww.com
Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in Nephrology and
Hypertension Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in …

Partial epithelial-to-mesenchymal transition and other new mechanisms of kidney fibrosis

S Lovisa, M Zeisberg, R Kalluri - Trends in Endocrinology & Metabolism, 2016 - cell.com
Kidney fibrosis is the unavoidable consequence of chronic kidney disease irrespective of the
primary underlying insult. It is a complex phenomenon governed by the interplay between …

Inflammatory mediators and renal fibrosis

XM Meng - Renal Fibrosis: Mechanisms and Therapies, 2019 - Springer
Renal inflammation is the initial, healthy response to renal injury. However, prolonged
inflammation promotes the fibrosis process, which leads to chronic pathology and eventually …

Novel insights into the pathogenesis of monogenic congenital anomalies of the kidney and urinary tract

AT van der Ven, A Vivante… - Journal of the American …, 2018 - journals.lww.com
Congenital anomalies of the kidneys and urinary tract (CAKUT) comprise a large spectrum
of congenital malformations ranging from severe manifestations, such as renal agenesis, to …

[HTML][HTML] Renal allograft fibrosis: biology and therapeutic targets

P Boor, J Floege - American journal of transplantation, 2015 - Elsevier
Renal tubulointerstitial fibrosis is the final common pathway of progressive renal diseases. In
allografts, it is assessed with tubular atrophy as interstitial fibrosis/tubular atrophy (IF/TA) …

Kidney development: two tales of tubulogenesis

M Little, K Georgas, D Pennisi, L Wilkinson - Current topics in …, 2010 - Elsevier
The mammalian kidney may well be one of the most complex organs of postnatal life. Each
adult human kidney contains on average more than one million functional filtration units, the …

[HTML][HTML] Human kidney pericytes produce renin

A Stefanska, C Kenyon, HC Christian, C Buckley… - Kidney international, 2016 - Elsevier
Pericytes, perivascular cells embedded in the microvascular wall, are crucial for vascular
homeostasis. These cells also play diverse roles in tissue development and regeneration as …