Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

As a non-classic major histocompatibility complex (MHC) class I molecule, human leukocyte
antigen G (HLA-G) is expressed in fetal-maternal interface and immunoprivileged site only in …

Background: Human leukocyte antigen (HLA)-G antigens are inducible non-classical major
histocompatibility complex class Ib molecules which play an important role in the regulation …

Human leukocyte antigens G and E (HLA-G and HLA-E) are nonclassical major
histocompatibility complex (MHC) class I molecules. These molecules play an important role …

Background Genetic factors have been found to be associated with the efficacy and adverse
reactions of antiseizure medications. BCL11A is an important regulator of the development …

Background HLA-G is associated with cancer cell escape. The 3'UTR polymorphism is
involved in the regulation of membrane-bound HLA-G and soluble HLA-G proteins. The aim …

Bipolar disorder (BD) is frequently associated with immune dysfunctions. Studying the
genetic diversity of the immuno-modulatory human leukocyte antigen (HLA)-G locus in a …

Aim: To evaluate the role of the HLA-G rs66554220 variant in NS-V and its clinical features
in Northwestern Mexicans. Material and methods: We genotyped the rs66554220 variant by …

Background Gastric cancer (GC) remains a serious health concern and is characterized by a
multifactorial etiology involving both genetic and epigenetic factors. The aim of the current …

Human leucocyte antigen-G (HLA-G) plays an important role in the progression of human
cancers. A growing number of published studies have investigated the correlation between …