Bioactive lipids, inflammation and chronic diseases

A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

The role of the gut microbiota in the pathogenesis of diabetes

W Bielka, A Przezak, A Pawlik - International journal of molecular …, 2022 - mdpi.com
Diabetes mellitus is a significant clinical and therapeutic problem because it can lead to
serious long-term complications. Its pathogenesis is not fully understood, but there are …

An updated review of pro-and anti-inflammatory properties of plasma lysophosphatidylcholines in the vascular system

E Knuplez, G Marsche - International Journal of Molecular Sciences, 2020 - mdpi.com
Lysophosphatidylcholines are a group of bioactive lipids heavily investigated in the context
of inflammation and atherosclerosis development. While present in plasma during …

[HTML][HTML] The role of the microbiome in diabetes mellitus

S Zhang, Y Cai, C Meng, X Ding, J Huang, X Luo… - diabetes research and …, 2021 - Elsevier
The microbiome is greatly significant for immune system development and homeostasis.
Dysbiosis in gut microbial composition and function is linked to immune responses and the …

Multi-omics profiling: the way toward precision medicine in metabolic diseases

C Hu, W Jia - Journal of molecular cell biology, 2021 - academic.oup.com
Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …

Ethnic disparities attributed to the manifestation in and response to type 2 diabetes: insights from metabolomics

S Vasishta, K Ganesh, S Umakanth, MB Joshi - Metabolomics, 2022 - Springer
Abstract Type 2 diabetes (T2D) associated health disparities among different ethnicities
have long been known. Ethnic variations also exist in T2D related comorbidities including …

The changes of lipidomic profiles reveal therapeutic effects of exenatide in patients with type 2 diabetes

L Zhang, Y Hu, Y An, Q Wang, J Liu… - Frontiers in …, 2022 - frontiersin.org
Objective Exenatide has been demonstrated beneficial effects on patients with type 2
diabetes mellitus (T2DM) regarding lipid metabolism. However, the potential mechanism …

Multiomics technologies: role in disease biomarker discoveries and therapeutics

MA Dar, A Arafah, KA Bhat, A Khan… - Briefings in …, 2023 - academic.oup.com
Medical research has been revolutionized after the publication of the full human genome.
This was the major landmark that paved the way for understanding the biological functions …

Postprandial metabolism is impaired in overweight normoglycemic young adults without family history of diabetes

AA Kumar, G Satheesh, G Vijayakumar, M Chandran… - Scientific Reports, 2020 - nature.com
While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of
transition from normal to a prediabetes state are unidentified. We studied the basal …

Lipidomics of the erythrocyte membrane and network pharmacology to explore the mechanism of mangiferin from Anemarrhenae rhizoma in treating type 2 diabetes …

Y Zhong, Y Xu, Y Tan, X Zhang, R Wang… - … of Pharmaceutical and …, 2023 - Elsevier
Mangiferin, a natural C-glucoside xanthone, is one of the major bioactive ingredients
derived from the dry rhizome of Anemarrhenae rhizome, which has been reported to exhibit …