Cation− π interaction: Its role and relevance in chemistry, biology, and material science

AS Mahadevi, GN Sastry - Chemical reviews, 2013 - ACS Publications
Noncovalent interactions are essential for the existence of solid and liquid phases. 1, 2
Traditionally touted as weak forces, quantification of these interactions, which govern the …

Alpha neurotoxins

CM Barber, GK Isbister, WC Hodgson - Toxicon, 2013 - Elsevier
α-Neurotoxins have been isolated from hydrophid, elapid and, more recently, colubrid snake
venoms. Also referred to as postsynaptic neurotoxins or 'curare mimetic'neurotoxins, they …

Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution

CD Dellisanti, Y Yao, JC Stroud, ZZ Wang… - Nature neuroscience, 2007 - nature.com
We determined the crystal structure of the extracellular domain of the mouse nicotinic
acetylcholine receptor (nAChR) α1 subunit bound to α-bungarotoxin at 1.94 Å resolution …

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α‐neurotoxins and nicotinic receptors

Y Bourne, TT Talley, SB Hansen, P Taylor… - The EMBO …, 2005 - embopress.org
The crystal structure of the snake long α‐neurotoxin, α‐cobratoxin, bound to the pentameric
acetylcholine‐binding protein (AChBP) from Lymnaea stagnalis, was solved from good …

Snake three-finger α-neurotoxins and nicotinic acetylcholine receptors: Molecules, mechanisms and medicine

S Nirthanan - Biochemical pharmacology, 2020 - Elsevier
Snake venom three-finger α-neurotoxins (α-3FNTx) act on postsynaptic nicotinic
acetylcholine receptors (nAChRs) at the neuromuscular junction (NMJ) to produce skeletal …

eat-2 and eat-18 Are Required for Nicotinic Neurotransmission in the Caenorhabditis elegans Pharynx

JP McKay, DM Raizen, A Gottschalk, WR Schafer… - Genetics, 2004 - academic.oup.com
Mutations in eat-2 and eat-18 cause the same defect in C. elegans feeding behavior: the
pharynx is unable to pump rapidly in the presence of food. EAT-2 is a nicotinic acetylcholine …

[HTML][HTML] Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications

VI Tsetlin, F Hucho - FEBS letters, 2004 - Elsevier
This review covers recent data on interactions of nicotinic acetylcholine receptors (AChR)
with snake venom proteins (α-and κ-neurotoxins,'weak'toxins recently shown to act on …

A Monomeric 310-Helix Is Formed in Water by a 13-Residue Peptide Representing the Neutralizing Determinant of HIV-1 on gp41,

Z Biron, S Khare, AO Samson, Y Hayek, F Naider… - Biochemistry, 2002 - ACS Publications
The peptide gp41659-671 (ELLELDKWASLWN) comprises the entire epitope for one of the
three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates …

Bridging the gap between Alzheimer's disease and Alzheimer's-like diseases in animals

A Gołaszewska, W Bik, T Motyl… - International journal of …, 2019 - mdpi.com
The average life span steadily grows in humans and in animals kept as pets or left in
sanctuaries making the issue of elderly-associated cognitive impairment a hot-spot for …

Short-chain consensus alpha-neurotoxin: a synthetic 60-mer peptide with generic traits and enhanced immunogenic properties

G de la Rosa, LL Corrales-García, X Rodriguez-Ruiz… - Amino Acids, 2018 - Springer
The three-fingered toxin family and more precisely short-chain α-neurotoxins (also known as
Type I α-neurotoxins) are crucial in defining the elapid envenomation process, but …