[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment

VMM Giménez, F Inserra, CD Tajer, J Mariani, L Ferder… - Life sciences, 2020 - Elsevier
COVID-19 pandemic has a high mortality rate and is affecting practically the entire world
population. The leading cause of death is severe acute respiratory syndrome as a …

[HTML][HTML] Melatonin and multiple sclerosis: Antioxidant, anti-inflammatory and immunomodulator mechanism of action

A Muñoz-Jurado, BM Escribano… - …, 2022 - Springer
Background Melatonin is an indole hormone secreted primarily by the pineal gland that
showing anti-oxidant, anti-inflammatory and anti-apoptotic capacity. It can play an important …

[HTML][HTML] Implications of oxidative stress and potential role of mitochondrial dysfunction in COVID-19: therapeutic effects of vitamin D

N de Las Heras, VM Martín Giménez, L Ferder… - Antioxidants, 2020 - mdpi.com
Due to its high degree of contagiousness and like almost no other virus, SARS-CoV-2 has
put the health of the world population on alert. COVID-19 can provoke an acute inflammatory …

The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions

T Behl, I Kaur, S Bungau, A Kumar, MS Uddin, C Kumar… - Life Sciences, 2020 - Elsevier
The novel corona virus disease has shaken the entire world with its deadly effects and rapid
transmission rates, posing a significant challenge to the healthcare authorities to develop …

Baseline vitamin D status, sleep patterns, and the risk of incident type 2 diabetes in data from the UK Biobank study

M Wang, T Zhou, X Li, H Ma, Z Liang… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Circulating vitamin D concentrations have been associated with the risk of type
2 diabetes (T2D), but the results are inconsistent. Emerging evidence suggests that vitamin …

[HTML][HTML] Melatonin as an anti-aging therapy for age-related cardiovascular and neurodegenerative diseases

VM Martín Giménez, N de Las Heras… - Frontiers in Aging …, 2022 - frontiersin.org
The concept of “aging” is defined as the set of gradual and progressive changes in an
organism that leads to an increased risk of weakness, disease, and death. This process may …

The shared molecular mechanisms underlying aging of the brain, major depressive disorder, and Alzheimer's disease: The role of circadian rhythm disturbances

M Amidfar, ML Garcez, YK Kim - Progress in Neuro-Psychopharmacology …, 2023 - Elsevier
An association with circadian clock function and pathophysiology of aging, major depressive
disorder (MDD), and Alzheimer's disease (AD) is well established and has been proposed …

Vitamin D receptor regulates transcription of mitochondrial DNA and directly interacts with mitochondrial DNA and TFAM

D Gezen-Ak, M Alaylıoğlu, Z Yurttaş, T Çamoğlu… - The Journal of …, 2023 - Elsevier
Vitamin D receptor (VDR) is an essential transcription factor (TF) synthesized in different cell
types. We hypothesized that VDR might also act as a mitochondrial TF. We conducted the …