Osteocytes and Primary Cilia

SW Verbruggen, A Sittichokechaiwut… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to provide a background on
osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing …

Skeletal adaptation to mechanical cues during homeostasis and repair: the niche, cells, and molecular signaling

PJ Atria, AB Castillo - Frontiers in Physiology, 2023 - frontiersin.org
Bones constantly change and adapt to physical stress throughout a person's life. Mechanical
signals are important regulators of bone remodeling and repair by activating skeletal stem …

[HTML][HTML] Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling

GP Johnson, S Fair, DA Hoey - Bone, 2021 - Elsevier
The benefits of physical loading to skeletal mass are well known. The primary cilium has
emerged as an important organelle in bone mechanobiology/mechanotransduction …

From Marrow to Bone and Fat: Exploring the Multifaceted Roles of Leptin Receptor Positive Bone Marrow Mesenchymal Stromal Cells

P Prasad, JA Cancelas - Cells, 2024 - mdpi.com
The bone marrow (BM) stromal cell microenvironment contains non-hematopoietic stromal
cells called mesenchymal stromal cells (MSCs). MSCs are plastic adherent, form CFU-Fs …

[HTML][HTML] Mechanobiology and Primary Cilium in the Pathophysiology of Bone Marrow Myeloproliferative Diseases

F Tiberio, ARD Coda, DD Tosi, D Luzi, L Polito… - International Journal of …, 2024 - mdpi.com
Philadelphia-Negative Myeloproliferative neoplasms (MPNs) are a diverse group of blood
cancers leading to excessive production of mature blood cells. These chronic diseases …

[HTML][HTML] 瘦素受体在小鼠皮肤中表达及瘦素受体阳性细胞在皮肤发育和创伤愈合中的作用

王傲, 褚宏尚, 吴红光, 李科, 刘慧娟 - 中国组织工程研究, 2022 - cjter.com
瘦素受体在小鼠皮肤中表达及瘦素受体阳性细胞在皮肤发育和创伤愈合中的作用 中国组织工程
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Understanding the Role of Skeletal Stem Cells in Load-Induced Bone Formation, Bone Repair, and Their Relationship With Angiogenesis

PJ Atria - 2024 - search.proquest.com
Understanding the role of skeletal stem cells in load-induced bone formation, bone repair, and
their relationship with angiogene Page 1 Understanding the role of skeletal stem cells in …

Making the Mold: A Microstructural Perspective on Bone Growth and Mechanical Adaptation through Bone Modeling

C Maggiano, I Maggiano - Bone Histology, 2025 - taylorfrancis.com
Popular conception is that bones grow at growth plates. In actuality, this is only true in
certain regions of a long bone during elongation. All other aspects of bone size, shape, and …

The design and synthesis of selective activators of Adenylyl Cyclase isoform 6 for the treatment of persistent pulmonary hypertension of the newborn

A Pritchard - 2023 - mspace.lib.umanitoba.ca
Abstract Persistent Pulmonary Hypertension of the Newborn (PPHN), is a condition that
reduces relaxation of blood vessels, which prevents a normal transition to independent …

[引用][C] THE PROS AND CONS OF FATIGUE LOADING OF BONE

D Hoey - Perspectives on the Mechanics of Fracture and …