Rotaviruses: From pathogenesis to disease control—A critical review

CA Omatola, AO Olaniran - Viruses, 2022 - mdpi.com
Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …

Current and new rotavirus vaccines

RM Burke, JE Tate, CD Kirkwood… - Current opinion in …, 2019 - journals.lww.com
Rotavirus vaccines have demonstrated impact in reducing diarrheal morbidity and mortality
worldwide. As countries begin to introduce the newly prequalified vaccines, additional data …

Vaccines for preventing rotavirus diarrhoea: vaccines in use

K Soares‐Weiser, H Bergman… - Cochrane database …, 2019 - cochranelibrary.com
Background Rotavirus results in more diarrhoea‐related deaths in children under five years
than any other single agent in countries with high childhood mortality. It is also a common …

Immunological factors linked to geographical variation in vaccine responses

MMAR van Dorst, JJ Pyuza, G Nkurunungi… - Nature Reviews …, 2024 - nature.com
Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …

Understanding rotavirus vaccine efficacy and effectiveness in countries with high child mortality

T Varghese, G Kang, AD Steele - Vaccines, 2022 - mdpi.com
Rotavirus claims thousands of lives of children globally every year with a disproportionately
high burden in low-and lower-middle income countries where access to health care is …

Rotavirus infection in children in Southeast Asia 2008–2018: disease burden, genotype distribution, seasonality, and vaccination

FB Lestari, S Vongpunsawad, N Wanlapakorn… - Journal of biomedical …, 2020 - Springer
Abstract Background Rotaviruses (RVs) are recognized as a major cause of acute
gastroenteritis (AGE) in infants and young children worldwide. Here we summarize the …

Efficacy of live oral rotavirus vaccines by duration of follow-up: a meta-regression of randomised controlled trials

A Clark, K van Zandvoort, S Flasche… - The Lancet Infectious …, 2019 - thelancet.com
Background The duration of protection offered by rotavirus vaccines varies across the world,
and this variation is important to understanding and predicting the effects of the vaccines …

Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants

AHJ Kim, G Armah, F Dennis, L Wang, R Rodgers… - Cell Host & Microbe, 2022 - cell.com
Rotavirus vaccines (RVVs) have substantially diminished mortality from severe rotavirus
(RV) gastroenteritis but are significantly less effective in low-and middle-income countries …

Rotavirus research: 2014–2020

S Caddy, G Papa, A Borodavka, U Desselberger - Virus research, 2021 - Elsevier
Rotaviruses are major causes of acute gastroenteritis in infants and young children
worldwide and also cause disease in the young of many other mammalian and of avian …

Development of high-throughput UPLC-MS/MS using multiple reaction monitoring for quantitation of complex human milk oligosaccharides and application to large …

J Li, Y Bi, Y Zheng, C Cao, L Yu, Z Yang, W Chai, J Yan… - Food Chemistry, 2022 - Elsevier
Human milk oligosaccharides (HMOs) have attracted increasing attention due to the
emerging evidence of their positive roles for infant's health. A high-throughput method for …