Quadruplex-forming sequences are widely prevalent in human and other genomes,
including bacterial ones. These sequences are over-represented in eukaryotic telomeres …

Quadruplex nucleic acids—helical four-stranded structures known to form from guanine-rich
nucleic acid sequences through Hoogsteen-type hydrogen bonding—were once just …

A curated library of circular dichroism spectra of 23 G‐quadruplexes of known structure was
built and analyzed. The goal of this study was to use this reference library to develop an …

A detailed knowledge of the complex processes that make cells and organisms alive is
fundamental in order to understand diseases and to develop novel drugs and therapeutic …

Telomeres are DNA-protein complexes that cap and protect the ends of linear
chromosomes. In almost all species, telomeric DNA has a G/C strand bias, and the short …

The quest for a G-quadruplex specific fluorescent sensor among other DNA forms under
physiological salt conditions has been addressed in this article. We demonstrate for the first …

Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids;
therefore, CD spectroscopy has been used to study most features of DNA and RNA …

Telomeres play an important role in cellular aging and cancer. Human telomeric DNA and
RNA G‐rich sequences are capable of forming a four‐stranded structure, known as the G …

Nucleic acid sequences containing several short runs of guanine nucleotides can form
complex higher order structures, termed quadruplexes. Their occurrence has been most …

Human telomeric G‐quadruplex DNA structures are attractive anticancer drug targets, but
the target's polymorphism complicates the drug design: different ligands prefer different …