Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with
high affinity and specificity. The process of selecting an aptamer is called Systematic …

Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Label-free optical biosensors are an intriguing option for the analyses of many analytes, as
they offer several advantages such as high sensitivity, direct and real-time measurement in …

Aptamers have become coming-of-age molecular recognition elements in both diagnostic
and therapeutic applications. Generated by SELEX, the 'quality control'of aptamers, which …

Direct optical detection has proven to be a highly interesting tool in biomolecular interaction
analysis to be used in drug discovery, ligand/receptor interactions, environmental analysis …

Recent progresses in organic chemistry and molecular biology have allowed the emergence
of numerous new applications of nucleic acids that markedly deviate from their natural …

During medical treatment it is critical to maintain the circulatory concentration of drugs within
their therapeutic range. A novel biosensor is presented in this work to address the lack of a …

Unraveling the complexities of brain function, which is crucial for advancing human health,
remains a grand challenge. This endeavor demands precise monitoring of small molecules …

Aptamer-based point-of-care (POC) diagnostics platforms may be of substantial benefit in
forensic analysis as they provide rapid, sensitive, user-friendly, and selective analysis tools …

Functional nucleic acids (FNAs) have emerged as superior molecular recognition elements
with high binding affinity, specificity, and catalytic activity. Due to multiple functionalities like …