Neonatal opioid withdrawal syndrome (NOWS) is a growing public health concern. The
complexity of in utero opioid exposure in clinical studies makes it difficult to investigate …

The opioid epidemic has received considerable attention, but the impact on perinatal opioid-
exposed (POE) offspring remains underexplored. This study addresses the emerging public …

Rationale In utero opioid exposure is associated with lower weight and a neonatal opioid
withdrawal syndrome (NOWS) at birth, along with longer-term adverse neurodevelopmental …

Nonmedical use of prescription opioids peaks during late adolescence, a developmental
period associated with the maturation of higher-order cognitive processes. To date …

Nationwide, opioid misuse among pregnant women has risen four-fold from 1999 to 2014,
with commensurate increase in neonates hospitalized for neonatal abstinence syndrome …

The rising prevalence of early-life opioid exposure has become a pressing public health
issue in the US Neonates exposed to opioids in utero are at risk of experiencing a …

Introduction The opioid epidemic has seen an increase in drug use among women of
reproductive age. It is well established that Opioid Use Disorder (OUD) can have many …

Researchers have found considerable evidence in the past 20 years that perinatal opioid
exposure leads to an increased risk of developmental disorders in offspring that persist into …

Endogenous opioid peptides and their receptors perform critical roles in reward, aversion,
and drug exposure processes. Both the peptides and the receptors perform distinct roles in …

Abstract The Opioid Epidemic has been a point of public health interest for the last twenty
years. In this time, use of prescription opioids has grown exponentially, including use by …