Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …

There is compelling clinical and experimental evidence to suggest that natural killer (NK)
cells play a critical role in the recognition and eradication of tumors. Efforts at using NK cells …

A key mechanism of tumor resistance to immune cells is mediated by expression of peptide-
loaded HLA class I molecule (HLA-E) in tumor cells, which suppresses NK cell activity via …

Tumor-infiltrating CD8 T cells were found to frequently express the inhibitory receptor
NKG2A, particularly in immune-reactive environments and after therapeutic cancer …

The leukocyte immunoglobulin-like receptor (LILR) family comprises a set of paired
immunomodulatory receptors expressed among human myeloid and lymphocyte cell …

Chronic inflammation in the tumor microenvironment and evasion of the antitumor effector
immune response are two of the emerging hallmarks required for oncogenesis and cancer …

In human tumors alterations in the surface expression and/or function of the major
histocompatibility complex (MHC) class I antigens are frequently found and equip neoplastic …

Purpose Monalizumab is a monoclonal antibody targeting the inhibitory natural killer group
2A (NKG2A) receptor localised on natural killer (NK) and T cells. Its ligand, the human …

Background: There remain a small number of patients with papillary thyroid cancer (PTC)
who suffer recurrence, metastases, or death. While mutation of the BRAF gene …

Purpose This study examines the tumour–host immune interactions in head and neck
squamous cell carcinoma (HNSCC) and their relationship to human papillomavirus (HPV) …