Hox genes, a highly conserved subgroup of the homeobox superfamily, have crucial roles in
development, regulating numerous processes including apoptosis, receptor signalling …

'Homeotic'transformations are developmental anomalies in which one part of the body
develops iiJ the likeness of another. Many cases of homeosis were described and the …

This paper reports the cloning of the fourth major murine homeogene complex, HOX‐5. The
partial characterization of this gene cluster revealed the presence of two novel genes (Hox …

In situ hybridization analysis of mouse embryos shows the seven members of the Hex-2
complex to be differentially expressed in the central and peripheral nervous system and in …

Abstract NEUROFIBROMATOSIS type 1 (NF1) is a common autosomal dominant disorder
with a high mutation rate and variable expression, characterized by neurofibromas, café-au …

THE branchial region of the vertebrate head forms through complex interactions involving
rhombomeric segments, neural crest and branchial arches1. It is thought that aspects of their …

In Drosophila, homeotic genes of the Antennapedia (ANTC) and Bithorax (BX-C) complexes
specify the distinctions between different segments of the body. Each of these genes …

A murine multigene family has been identified that shares a conserved sequence motif, the
paired box, with developmental control and tissue-specific genes of Drosophila. To date five …

Databases have revolutionized nearly every aspect of our lives. Information of all sorts is
being collected on a massive scale, from Google to Facebook and well beyond. But as the …

The vertebrate hindbrain develops in a segmental pattern, with distinctive groups of neurons
originating from different segments. We report here that members of the Hox-2 cluster of …