Background Liver disease is the major cause of serious health problem leading to morbidity
and mortality worldwide and the problem has increased in search for hepatotherapeutic …

Nephrotoxicity is of critical concern when selecting new drug candidates during the early
stage of drug development. Because of its unique metabolism, the kidney is an important …

Objectives The aim of the study was to investigate the renoprotective effect of hesperidin
(HDN), a citrus flavanoid with anti-oxidant properties against gentamicin (GEN)-induced …

Objective: Cadmium is an environmental pollutant that ranked as one of the top toxic
substances rampant in many industries such as cement plants and smoke, batteries and …

Rationale: Kidneys are dynamic organs and represent one of the major systems maintaining
the body homeostasis; they are affected by many chemicals and drugs. Grape seed extract …

Amikacin is an important antibiotic, and its use is limited because of the induced
nephrotoxicity. Thus, search for natural and synthetic agents that can moderate amikacin …

One of the most efficient aminoglycoside is amikacin. Yet, it has been linked to unwanted
renal toxicity, which has resulted in negative alterations in various biochemical indicators …

Arsenic is considered one of the major environmental toxic metals causing male infertility.
The objective of the present study was to evaluate the toxic effects of arsenic trioxide on the …

To date, there is no specific treatment used to protect against gentamicin (Genta)-induced
nephrotoxicity. The main objective of the present study was to determine the potential …

Gentamicin is a widely employed antibiotic, but may reduce calcium uptake by eukaryotic
cells. This study was conducted to determine whether gentamicin reduces calcification by …