The continuous emergence and rapid spread of a multidrug-resistant strain of bacterial
pathogens have demanded the discovery and development of new antibacterial agents. A …

Similar to its eukaryotic counterpart, the prokaryotic cytoskeleton is essential for the
structural and mechanical properties of bacterial cells. The essential protein FtsZ is a central …

Epigallocatechin gallate (EGCG) is a polyphenol present in green tea (Camellia sinensis),
which has revealed anti-cancer effects toward a variety of cancer cells in vitro and protective …

The disturbing increase in the number of bacterial pathogens that are resistant to multiple, or
sometimes all, current antibiotics highlights the desperate need to pursue the discovery and …

Inhibition of the functional activity of Filamenting temperature-sensitive mutant Z (FtsZ)
protein, an essential and highly conserved bacterial cytokinesis protein, is a promising …

Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public
health. Thus, identification of new targets and development of new antibacterial agents are …

Binary fission is the most common mode of bacterial cell division and is mediated by a
multiprotein complex denominated the divisome. The constriction of the Z-ring splits the …

With the emergence of multidrug-resistant bacterial strains, there is a dire need for new drug
targets for antibacterial drug discovery and development. Filamentous temperature sensitive …

In recent years, the rise of antibiotic resistance has become a primary health problem. With
the emergence of bacterial resistance, the need to explore and develop novel antibacterial …

Proteins involved in bacterial cell division often do not have a counterpart in eukaryotic cells
and they are essential for the survival of the bacteria. The genetic accessibility of many …