Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

[HTML][HTML] An updated overview on the relationship between human gut microbiome dysbiosis and psychiatric and psychological disorders

A Borrego-Ruiz, JJ Borrego - Progress in Neuro-Psychopharmacology and …, 2024 - Elsevier
There is a lot of evidence establishing that nervous system development is related to the
composition and functions of the gut microbiome. In addition, the central nervous system …

Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management

A Bhangu, K Søreide, S Di Saverio, JH Assarsson… - The Lancet, 2015 - thelancet.com
Acute appendicitis is one of the most common abdominal emergencies worldwide. The
cause remains poorly understood, with few advances in the past few decades. To obtain a …

[HTML][HTML] Akkermansia muciniphila in the human gastrointestinal tract: when, where, and how?

SY Geerlings, I Kostopoulos, WM De Vos, C Belzer - Microorganisms, 2018 - mdpi.com
Akkermansia muciniphila is a mucin-degrading bacterium of the phylum Verrucomicrobia. Its
abundance in the human intestinal tract is inversely correlated to several disease states. A …

Of men in mice: the development and application of a humanized gnotobiotic mouse model for microbiome therapeutics

JC Park, SH Im - Experimental & molecular medicine, 2020 - nature.com
Considerable evidence points to the critical role of the gut microbiota in physiology and
disease. The administration of live microbes as a therapeutic modality is increasingly being …

Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ

CM Guinane, PD Cotter - Therapeutic advances in …, 2013 - journals.sagepub.com
The human gut microbiota has become the subject of extensive research in recent years and
our knowledge of the resident species and their potential functional capacity is rapidly …

Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health …

M Collard, Z Lakkis, J Loriau, D Mege… - Journal of visceral …, 2020 - Elsevier
The massive inflow of patients with COVID-19 requiring urgent care has overloaded
hospitals in France and impacts the management of other patients. Deferring hospitalization …

The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new …

SM Vindigni, TL Zisman, DL Suskind… - Therapeutic …, 2016 - journals.sagepub.com
We discuss the tripartite pathophysiological circuit of inflammatory bowel disease (IBD),
involving the intestinal microbiota, barrier function, and immune system. Dysfunction in each …

Colon cancer: from epidemiology to prevention

K Katsaounou, E Nicolaou, P Vogazianos, C Brown… - Metabolites, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most prevalent cancers affecting humans, with a
complex genetic and environmental aetiology. Unlike cancers with known environmental …

Role of microbiota-derived metabolites in alcoholic and non-alcoholic fatty liver diseases

JW Park, SE Kim, NY Lee, JH Kim, JH Jung… - International Journal of …, 2021 - mdpi.com
Chronic liver disease encompasses diseases that have various causes, such as alcoholic
liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Gut microbiota …