An update on pharmacological potential of boswellic acids against chronic diseases

NK Roy, D Parama, K Banik, D Bordoloi… - International journal of …, 2019 - mdpi.com
Natural compounds, in recent years, have attracted significant attention for their use in the
prevention and treatment of diverse chronic diseases as they are devoid of major toxicities …

DNA methyltransferases: a novel target for prevention and therapy

D Subramaniam, R Thombre, A Dhar, S Anant - Frontiers in oncology, 2014 - frontiersin.org
Cancer is the second leading cause of death in US. Despite the emergence of new, targeted
agents, and the use of various therapeutic combinations, none of the available treatment …

Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities

T Efferth, F Oesch - Seminars in cancer biology, 2022 - Elsevier
The oleogum resins of Boswellia species known as frankincense have been used for ages
in traditional medicine in India, China and the Arabian world independent of its use for …

Identification of potential key genes associated with the pathogenesis and prognosis of gastric cancer based on integrated bioinformatics analysis

X Liu, J Wu, D Zhang, Z Bing, J Tian, M Ni… - Frontiers in …, 2018 - frontiersin.org
Background and Objective: Despite striking advances in multimodality management, gastric
cancer (GC) remains the third cause of cancer mortality globally and identifying novel …

Epigenetics of colorectal cancer

A Goel, CR Boland - Gastroenterology, 2012 - Elsevier
In the early years of the molecular biology revolution, cancer research was mainly focused
on genetic changes (ie, those that altered DNA sequences). Although this has been …

The journey of boswellic acids from synthesis to pharmacological activities

EA Ragab, MF Abd El-Wahab, AS Doghish… - Naunyn-schmiedeberg's …, 2024 - Springer
There has been a lot of interest in using naturally occurring substances to treat a wide
variety of chronic disorders in recent years. From the gum resin of Boswellia serrata and …

Natural bioactive compounds targeting epigenetic pathways in cancer: a review on alkaloids, terpenoids, quinones, and isothiocyanates

N El Omari, S Bakrim, M Bakha, JM Lorenzo… - Nutrients, 2021 - mdpi.com
Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …

Curcumin modulates DNA methylation in colorectal cancer cells

A Link, F Balaguer, Y Shen, JJ Lozano, HCE Leung… - PloS one, 2013 - journals.plos.org
Aim Recent evidence suggests that several dietary polyphenols may exert their
chemopreventive effect through epigenetic modifications. Curcumin is one of the most …

DNA methyltransferase-1 inhibitors as epigenetic therapy for cancer

V Singh, P Sharma, N Capalash - Current cancer drug targets, 2013 - ingentaconnect.com
DNA methylation is an epigenetic modification involved in gene expression regulation. In
cancer, the DNA methylation pattern becomes aberrant, causing an array of tumor …

Googling the Guggul (Commiphora and Boswellia) for prevention of chronic diseases

AB Kunnumakkara, K Banik, D Bordoloi… - Frontiers in …, 2018 - frontiersin.org
Extensive research during last 2 decades has revealed that most drugs discovered today,
although costs billions of dollars for discovery, and yet they are highly ineffective in their …