Podoplanin in inflammation and cancer

M Quintanilla, L Montero-Montero, J Renart… - International journal of …, 2019 - mdpi.com
Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

[HTML][HTML] Biological, chemical and mechanical factors regulating migration and homing of mesenchymal stem cells

R Szydlak - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are a population of primary and non-specialized cells,
which can be isolated from various tissues. Currently, MSCs are key players in cellular …

Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury

Q Sastourné-Arrey, M Mathieu, X Contreras… - Nature …, 2023 - nature.com
Fibro-adipogenic progenitors (FAPs) play a crucial role in skeletal muscle regeneration, as
they generate a favorable niche that allows satellite cells to perform efficient muscle …

Bisphenol A and 2, 3, 7, 8‐tetrachlorodibenzo‐p‐dioxin at non‐cytotoxic doses alter the differentiation potential and cell function of rat adipose‐stem cells

HC Nunes, SC Tavares, HV Garcia… - Environmental …, 2022 - Wiley Online Library
The possibility of chemical contamination is an important issue to consider when designing
a cell therapy strategy. Both bisphenol A (BPA) and 2, 3, 7, 8‐tetrachlorodibenzo‐p‐dioxin …

Cell motility and migration as determinants of stem cell efficacy

L Danielyan, M Schwab, G Siegel, B Brawek… - …, 2020 - thelancet.com
Background Stem cells(SC) functional heterogeneity and its poorly understood aetiology
impedes clinical development of cell-based therapies in regenerative medicine and …

[HTML][HTML] Endogenous mobilization of mesenchymal stromal cells: a pathway for interorgan communication?

A Girousse, M Mathieu, Q Sastourné-Arrey… - Frontiers in Cell and …, 2021 - frontiersin.org
To coordinate specialized organs, inter-tissue communication appeared during evolution.
Consequently individual organs communicate their states via a vast interorgan …

Podoplanin regulates the migration of mesenchymal stromal cells and their interaction with platelets

LSC Ward, L Sheriff, JL Marshall… - Journal of cell …, 2019 - journals.biologists.com
Mesenchymal stromal cells (MSCs) upregulate podoplanin at sites of infection, chronic
inflammation and cancer. Here, we investigated the functional consequences of podoplanin …

[HTML][HTML] Synovial gene signatures associated with the development of rheumatoid arthritis in at risk individuals: A prospective study

TA de Jong, MJH de Hair, MGH van de Sande… - Journal of …, 2022 - Elsevier
Objective To identify molecular changes in synovium before arthritis development in
individuals at risk of developing rheumatoid arthritis (RA). Materials and methods We …

Mesenchymal stem cells in the treatment of COVID-19, a promising future

DG Beghini, SI Horita, A Henriques-Pons - Cells, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent adult stem cells present in virtually all
tissues; they have a potent self-renewal capacity and can differentiate into multiple cell …

Mesenchymal stem cells as endogenous regulators of inflammation

H Munir, LSC Ward, HM McGettrick - Stromal Immunology, 2018 - Springer
This chapter discusses the regulatory role of endogenous mesenchymal stem cells (MSC)
during an inflammatory response. MSC are a heterogeneous population of multipotent cells …