[HTML][HTML] Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion

W Toller, M Heringlake, F Guarracino… - International Journal of …, 2015 - Elsevier
In cardiac surgery, postoperative low cardiac output has been shown to correlate with
increased rates of organ failure and mortality. Catecholamines have been the standard …

Levosimendan reduces mortality and low cardiac output syndrome in cardiac surgery

C Weber, M Esser, K Eghbalzadeh… - The Thoracic and …, 2020 - thieme-connect.com
Background There has been conflicting evidence concerning the effect of levosimendan on
clinical outcomes in patients undergoing cardiac surgery. Therefore, we performed a …

Levosimendan for perioperative cardioprotection: myth or reality?

E Santillo, M Migale, C Massini… - Current Cardiology …, 2018 - ingentaconnect.com
Background: Levosimendan is a calcium sensitizer drug causing increased contractility in
the myocardium and vasodilation in the vascular system. It is mainly used for the therapy of …

[PDF][PDF] S3-Leitlinie zur intensivmedizinischen Versorgung herzchirurgischer Patienten: Hämodynamisches Monitoring und Herz-Kreislauf–ein Update

M Habicher, T Zajonz, M Heringlake, A Böning… - Anaesthesist, 2018 - researchgate.net
Die erneute Aktualisierung der Leitlinie beinhaltete wiederum eine erneute systematische
Literaturrecherche nach den gleichen Vorgaben, die den Zeitraum von November 2009 bis …

A randomized controlled trial of levosimendan to reduce mortality in high-risk cardiac surgery patients (CHEETAH): Rationale and design

A Zangrillo, G Alvaro, A Pisano, F Guarracino… - American Heart …, 2016 - Elsevier
Objective Patients undergoing cardiac surgery are at risk of perioperative low cardiac output
syndrome due to postoperative myocardial dysfunction. Myocardial dysfunction in patients …

Early levosimendan administration is associated with decreased mortality after cardiac surgery

S Treskatsch, F Balzer, T Geyer, CD Spies… - Journal of critical …, 2015 - Elsevier
Purpose The aim of this study was to assess the effects on postoperative outcome of
levosimendan with respect to timing of its administration in cardiac surgery patients …

Levosimendan: mechanistic insight and its diverse future aspects in cardiac care

MS Akhtar, MQ Hassan, A Siddiqui… - Acta …, 2023 - Taylor & Francis
Inotropic agents are generally recommended to use in patients with acute decompensated
heart failure (HF) with reduced ejection fraction (HFrEF) concurrent to end-organ …

A randomized blinded study of the left ventricular myocardial performance index comparing epinephrine to levosimendan following cardiopulmonary bypass

MF Salgado Filho, M Barral, L Barrucand… - PLoS …, 2015 - journals.plos.org
Background The objective was to evaluate the effect of epinephrine and levosimendan on
the left ventricle myocardial performance index in patients undergoing on-pump coronary …

Levosimendan use increases cardiac performance after coronary artery bypass grafting in end-stage renal disease patients

H Atalay, Z Temizturk, HB Altinsoy… - The Heart Surgery …, 2016 - journal.hsforum.com
Background: The effect of levosimendan on myocardial performance has not been studied in
dialysis-dependent end-stage renal disease patients who have undergone coronary artery …

Early-term results of early coronary artery bypass graft surgery in patients undergoing primary percutaneous coronary intervention due to acute coronary syndrome

AK As, M Engin, T Turk - The European Research Journal, 2020 - dergipark.org.tr
Objectives: This study aimed to investigate the early results of the patients presented with
acute coronary syndrome (ACS) who underwent coronary artery bypass grafting (CABG) …