Cell-based therapeutic strategies for multiple sclerosis

NJ Scolding, M Pasquini, SC Reingold, JA Cohen - Brain, 2017 - academic.oup.com
The availability of multiple disease-modifying medications with regulatory approval to treat
multiple sclerosis illustrates the substantial progress made in therapy of the disease …

Mesenchymal stromal cells (MSCs) for neurodegenerative disease: a promising frontier

A Shariati, R Nemati, Y Sadeghipour… - European journal of cell …, 2020 - Elsevier
Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD),
Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic …

Bone marrow stromal stem cells in tissue engineering and regenerative medicine

A Polymeri, WV Giannobile… - Hormone and Metabolic …, 2016 - thieme-connect.com
Bone marrow stromal stem cells (BMSCs) are adult multipotent cells, which have the
potential to differentiate into cell types of mesodermal origin, namely osteocytes, adipocytes …

Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases

E Ben-Ami, S Berrih-Aknin, A Miller - Autoimmunity reviews, 2011 - Elsevier
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent progenitor cells which
can be isolated from various human adult tissues. In recent years, MSCs have been shown …

Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells

JC Ra, SK Kang, IS Shin, HG Park, SA Joo… - Journal of translational …, 2011 - Springer
Prolonged life expectancy, life style and environmental changes have caused a changing
disease pattern in developed countries towards an increase of degenerative and …

Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis

JA Cohen, PB Imrey, SM Planchon… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Mesenchymal stem cells (MSCs) exhibit immunomodulatory, tissue-protective,
and repair-promoting properties in vitro and in animals. Clinical trials in several human …

Mesenchymal stem cell transplantation in multiple sclerosis

JA Cohen - Journal of the neurological sciences, 2013 - Elsevier
Mesenchymal stem cells (MSCs) are pluripotent non-hematopoietic precursor cells that can
be isolated from bone marrow and numerous other tissues, culture-expanded to purity, and …

Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis

J Liang, H Zhang, B Hua, H Wang… - Multiple Sclerosis …, 2009 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system.
Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted …

Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report

S Guiducci, F Porta, R Saccardi, S Guidi… - Annals of internal …, 2010 - acpjournals.org
Background: Mesenchymal stem cells can differentiate into endothelial cells and participate
in angiogenesis in adults. In experimental models of acute myocardial infarction …

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks

A Tyndall, A Uccelli - Bone marrow transplantation, 2009 - nature.com
MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for
the treatment of autoimmune disease (AD) on the basis of their in vitro antiproliferative …