Maintaining genome integrity during cell division requires regulated interactions between
chromosomes and spindle microtubules. To ensure that daughter cells inherit the correct …

The mitosis-to-interphase transition involves dramatic cellular reorganization from a state
that supports chromosome segregation to a state that complies with all functions of an …

Increased crop yields are required to support rapid population growth worldwide. Grain
weight is a key component of rice yield, but the underlying molecular mechanisms that …

Regulated interactions between kinetochores and spindle microtubules are essential to
maintain genomic stability during chromosome segregation. The Aurora B kinase …

Protein serine/threonine phosphatases (PPPs) are ancient enzymes, with distinct types
conserved across eukaryotic evolution. PPPs are segregated into types primarily on the …

Faithful chromosome segregation during mitosis is essential for genome integrity and is
mediated by the bi-oriented attachment of replicated chromosomes to spindle microtubules …

Kinetochores connect centromeric nucleosomes with mitotic-spindle microtubules through
conserved, cross-interacting protein subassemblies. In budding yeast, the heterotetrameric …

Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and
regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man: PP1 …

Mitosis requires precise coordination of multiple global reorganizations of the nucleus and
cytoplasm. Cyclin-dependent kinase 1 (Cdk1) is the primary upstream kinase that directs …

CDC14 was originally identified by L. Hartwell in his famous screen for genes that regulate
the budding yeast cell cycle. Subsequent work showed that Cdc14 belongs to a family of …